Clinical Trials in Cleveland

Showing 11161-11180 of 16,969 trials

Tetra-O-Methyl Nordihydroguaiaretic Acid in Treating Patients With Recurrent High-Grade Glioma

NCT00404248

RATIONALE: Drugs used in chemotherapy, such as tetra-O-methyl nordihydroguaiaretic acid (EM-1421), work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. PURPOSE: This phase I/II trial is studying the side effects and best dose of EM-1421 and to see how well it works in treating patients with recurrent high-grade glioma.

Brain and Central Nervous System Tumors

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins35 participantsStarted Jan 2007

Birmingham, Alabama, United States • Tampa, Florida, United States • Atlanta, Georgia, United States +6 more locations

TERMINATEDPhase 4< 1 mile

Tolerability, Safety, and Feasibility of Naloxegol in Patients With Cancer and OIC (Opioid Induced Constipation)

NCT02839889

The purpose of this study is to determine if naloxegol can be used in the treatment of opioid-induced constipation in patients with cancer and pain. This phase 4 study consists of a two week randomized double blind period followed by a two week open-label period.

CancerConstipationPain

Hospice of Henderson County, Inc.12 participantsStarted Sep 2016

New York, New York, United States • Flat Rock, North Carolina, United States • Cleveland, Ohio, United States

Tetra-O-Methyl Nordihydroguaiaretic Acid in Treating Patients With Recurrent High-Grade Glioma

Tolerability, Safety, and Feasibility of Naloxegol in Patients With Cancer and OIC (Opioid Induced Constipation)

Find Trials by Condition in Cleveland

Propaten Randomized Investigation on Cost-benefit and Efficacy

Naltrexone for Use in Conjunction With Buprenorphine in Adults With Opioid Use Disorder Prior to First Dose of VIVITROL® (Naltrexone for Extended-Release Injectable Suspension)

Safety and Efficacy of Sofosbuvir/Velpatasvir/Voxilaprevir and Sofosbuvir/Velpatasvir in Adults With Chronic HCV Infection Who Have Not Previously Received Treatment With Direct-Acting Antiviral Therapy

VL-2397 Compared to Standard First-Line Treatment for Invasive Aspergillosis (IA) in Adults

Comparative Investigation of Low Molecular Weight (LMW) Heparin/Edoxaban Tosylate (DU176b) Versus (LMW) Heparin/Warfarin in the Treatment of Symptomatic Deep-Vein Blood Clots and/or Lung Blood Clots. (The Edoxaban Hokusai-VTE Study).

Post Approval Study of the TS Feature With the 530G Pump System Supplemented With Commercial Patient Data

Inflammation and the Host Response to Injury (Trauma)

Effect of Intramyocardial Injection of Mesenchymal Precursor Cells on Heart Function in People Receiving an LVAD

ExAblate UF V2 System for the Treatment of Symptomatic Uterine Fibroids

Evaluation of a Single Vaccination With One of Three Ascending Dose Levels of a 4-Antigen Staphylococcus Aureus Vaccine (SA4Ag) in Healthy Adults Aged 18 to <65 Years

Multicenter Benchmarking of Functional and Psychosocial Outcomes of Pediatric Burn Survivors

Safety and Efficacy Study of Herpes Simplex Virus Type 2 (HSV-2) Therapeutic DNA Vaccine

Safety and Efficacy Trial of DNA Vaccines to Treat Genital Herpes in Adults

Long-term Follow-up Study of Subjects Who Completed Clinical Studies 755.1100_FA, 810.1100_FA, or 1064.1100_FA

Project LIFT - Promoting Healthy Behavior Through a Wearable Fitness Device and Financial Incentives

An Open-Label Safety Study of API 31510 in a Topical Cream for in Situ Cutaneous Squamous Cell Carcinoma (SCCIS)

Validation of Non-Invasive Intracranial Pressure (ICP) Monitoring Device

Safety and Dose Ranging Study of Samalizumab to Treat Relapsing or Refractory CLL or MM