Clinical Trials in Cleveland

Showing 8481-8500 of 19,775 trials

SQ53 Disinfectant Wipes for Prevention of CRBSI

NCT04822467

SQ53 is a novel antimicrobial, sporicidal solution that is based on a platform of quaternary ammonium chloride compounds. It has been tested against a wide range of bacteria, viruses, spores and fungal pathogens. Extensive laboratory testing has demonstrated the effectiveness of SQ53 impregnated wipes in cleaning surfaces including catheters over a 24 hour plus time period. SQ53 also received an in vitro evaluation of the irritancy potential using a tissue engineered human skin model and was found to have no potential for skin irritation. SQ53 is available as a sterilized pack with a single wipe inside. The pack is easy to open by tearing off the top end and presenting the contents to the operator to remove under sterile conditions. The current study will be a randomized single-blinded placebo-controlled clinical trial for SQ53 wipes intended for catheter cleaning in patients receiving home parenteral nutrition.

Catheter-related Bloodstream Infection

The Cleveland Clinic59 participantsStarted Dec 2021

Cleveland, Ohio, United States

WITHDRAWNPhase 1< 1 mile

Single-Ascending Dose Study of JK07 in Subjects With HFpEF

NCT05322616

A phase 1, randomized, double-blind, placebo-controlled single-ascending dose study to assess JK07 in adult subjects with heart failure with preserved ejection fraction.

Heart Failure With Preserved Ejection Fraction

Salubris Biotherapeutics IncStarted Oct 2022

Stanford, California, United States • Boston, Massachusetts, United States • Rochester, Minnesota, United States +4 more locations

SQ53 Disinfectant Wipes for Prevention of CRBSI

Single-Ascending Dose Study of JK07 in Subjects With HFpEF

Find Trials by Condition in Cleveland

Effects of a Dietary Supplement Containing Salacia Extract, Citrus Bioflavonoids, and Trivalent Chromium on Markers of Glucose Control

Vedolizumab in the Prophylaxis of Intestinal Acute Graft Versus Host Disease (aGVHD) in Participants Undergoing Allogeneic Hematopoietic Stem Cell (Allo-HSCT) Transplantation

A Phase 4 Study of Efficacy and Safety of Apremilast in Subjects With Moderate Plaque Psoriasis.

BRITEPath- Phase 2

Convalescent Plasma to Limit SARS-CoV-2 Associated Complications

Clinical Evaluation of Two Daily Disposable Toric Soft Contact Lenses Over One Week of Wear

Pharmacokinetics and Safety of Ceftobiprole in Neonates and Infants up to 3 Months Treated With Systemic Antibiotics

An Open-label Study of ALPN-202 in Subjects With Advanced Malignancies

Live Biotherapeutic Product MRx0518 and Pembrolizumab Combination Study in Solid Tumors

Opioid Analgesic Reduction Study (OARS) - Pilot

A Study of Nivolumab or Nivolumab Plus Experimental Medication BMS-986205 With or Without Bacillus Calumette-Guerin (BCG) in BCG Unresponsive Bladder Cancer That Has Not Invaded Into the Muscle Wall of the Bladder

A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Immune Globulin (Human) 10% (Gamunex-C) PEG Process (IVIG-PEG) Compared to Gamunex-C in Participants With Primary Humoral Immunodeficiency

International Hernia Mesh Registry

Study of Safety & Effectiveness of PRESTIGE® LP Cervical Disc vs. Anterior Cervical Fusion in Cervical DDD

Evaluation of Updated Continuous Glucose Monitoring (CGM) Form Factor in Adults, Adolescents and Pediatrics

A Randomized, Controlled Trial of Ganaxolone in Patients With Infantile Spasms

A Phase 1b Study Evaluating the Safety and Tolerability of ABT-199 in Combination With Rituximab in Subjects With Relapsed Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma

EMB-01 in Combination With Osimertinib in Patients With EGFR Mutant Lung Cancer