Clinical Trials in Cleveland

Showing 8461-8480 of 15,050 trials

A Study Evaluating the Safety of VX-152 Combination Therapy in Adults With Cystic Fibrosis

NCT02951195

This is a Phase 2, randomized, double blind, placebo and active-controlled, parallel group, multicenter study designed to evaluate the safety and tolerability of VX-152 in Triple Combination (TC) with tezacaftor (TEZ; VX-661) and ivacaftor (IVA; VX-770) in subjects with cystic fibrosis (CF) who are heterozygous for the F508del mutation and a minimal function (MF) CFTR mutation not likely to respond to TEZ and/or IVA therapy (F508del/MF), or who are homozygous for the F508del mutation of the CF transmembrane conductance regulator (CFTR) gene (F508del/F508del).

Cystic Fibrosis

Vertex Pharmaceuticals Incorporated80 participantsStarted Nov 2016

Birmingham, Alabama, United States • La Jolla, California, United States • Los Angeles, California, United States +13 more locations

TERMINATEDPhase 3< 1 mile

S1222 Trial (Everolimus, Anastrozole and Fulvestrant) in Post-Menopausal Stage IV Breast Cancer

NCT02137837

This randomized Phase III trial studies how well the combination of fulvestrant and everolimus together or the combination of anastrozole, fulvestrant and everolimus together, improve progression-free survival (PFS) versus fulvestrant alone.

Breast Cancer

SWOG Cancer Research Network37 participantsStarted May 2014

Anchorage, Alaska, United States • Anchorage, Alaska, United States • Anchorage, Alaska, United States +220 more locations

A Study Evaluating the Safety of VX-152 Combination Therapy in Adults With Cystic Fibrosis

S1222 Trial (Everolimus, Anastrozole and Fulvestrant) in Post-Menopausal Stage IV Breast Cancer

Find Trials by Condition in Cleveland

Evaluation of Immunogenicity and Safety of VARIVAX® Passage Extension 34 (PE34) Process in Children (V210-A03)

Effect of Detrol LA on Overactive Bladder Symptoms, Sexual Quality of Life and Sexual Function in Women

Effect and Safety Of Detrol LA In Men With Overactive Bladder Symptoms With Or Without Bladder Outlet Obstruction

ACT34-CMI -- Adult Autologous CD34+ Cells

Evaluating the Impact of Video Discharge Instructions for Mohs Surgery Post-Operative Care

Beta-Blockers for the Prevention of Acute Exacerbations of Chronic Obstructive Pulmonary Disease

Care Optimization Through Patient and Hospital Engagement Clinical Trial for Heart Failure

Placebo-controlled Safety and Efficacy Study of Pregabalin in Subjects With Post-traumatic Peripheral Neuropathic Pain

ENABLE MRI (Magnetic Resonance Imaging)

Safety Study of Eteplirsen to Treat Early Stage Duchenne Muscular Dystrophy

Study of the Intravitreal Plasma Kallikrein Inhibitor, KVD001, in Subjects With Center-involving Diabetic Macular Edema (ciDME)

Efficacy and Safety of Eletriptan for the Treatment of Migraine in Patients Not Satisfied With Rizatriptan Therapy

The AdAPT Trial; Adenovirus After Allogeneic Pediatric Transplantation

Prospective Comparison of the Tuberculin Skin Test and Interferon-Gamma Release Assays in Diagnosing Infection With Mycobacterium Tuberculosis and in Predicting Progression to Tuberculosis

LBH589 in Relapsed or Relapsed and Refractory Waldenstrom's Macroglobulinemia

Study to Evaluate the Pharmacokinetics of Selonsertib in Participants With Normal and Impaired Hepatic Function

Amlodipine/Atorvastatin Combination to Reduce the Health Risk of High Blood Pressure and High Cholesterol Levels

Study Of The Safety And Efficacy Of Lyrica In The Treatment Of Newly Diagnosed Partial Epilepsy