Clinical Trials in Cleveland

Showing 681-700 of 19,775 trials

Virtual Patient Groups for Sarcoidosis Associated Fatigue

NCT07073963

This research study is testing whether Mindfulness-Based Stress Reduction (MBSR) can help reduce fatigue in people with sarcoidosis. The study will also look at whether MBSR can improve symptoms of anxiety and depression. Participants will be placed into one of two groups: * One group will take part in an 8-week virtual MBSR program, attend weekly online sessions, keep a daily mindfulness journal, and complete surveys about fatigue, anxiety, and depression. * The other group will join a virtual support group once a month for 5 months and complete the same surveys. The goal is to see which approach is more helpful for improving fatigue and mental well-being in people with sarcoidosis.

SarcoidosisFatigueDepression+2 more

The Cleveland Clinic100 participantsStarted Feb 2026

Cleveland, Ohio, United States

RECRUITINGPhase 3< 1 mile

A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease

NCT06612268

This study is conducted to confirm whether etavopivat works well at reducing the number of Vaso-occlusive crisis VOCs (sickle cell pain crises) caused by obstructions in blood vessels in adults and adolescents living with sickle cell disease. The study will also evaluate how well etavopivat can reduce the damage to different organs, improve your exercise tolerance and reduce fatigue in people with sickle cell disease.The participants will either get etavopivat or placebo. Which treatment the participants will get is decided by chance. Etavopivat is a new medicine and is currently being tested in other studies in addition to this one. The study will last for about 2 years.

Sickle Cell Disease

Novo Nordisk A/S408 participantsStarted Feb 2025

Birmingham, Alabama, United States • Mobile, Alabama, United States • Phoenix, Arizona, United States +169 more locations

Virtual Patient Groups for Sarcoidosis Associated Fatigue

A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease

Find Trials by Condition in Cleveland

Nivolumab After Surgery and Chemotherapy in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer (An ALCHEMIST Treatment Trial)

ONC-392 Versus Docetaxel in Metastatic NSCLC That Progressed on PD-1/PD-L1 Inhibitors

Bupropion Hydrochloride in Improving Sexual Desire in Women With Breast or Gynecologic Cancer

A Study to Evaluate the Pharmacokinetics, Safety, and Effectiveness of Certolizumab Pegol in Children With Moderate to Severe Chronic Plaque Psoriasis

A Study to Test Whether Survodutide (BI 456906) Helps People Living With Overweight or Obesity Who Also Have Diabetes to Lose Weight

DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment

Safety and Efficacy Study of VIS649 for IgA Nephropathy

A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and at Least One Weight-Related Comorbidity

A Study of the Safety and Efficacy of Various Combinations of Avelumab as Therapy in Locally Advanced or Metastatic Urothelial Carcinoma (JAVELIN Bladder Medley)

EXtubation Related Complications - the EXTUBE Study (EXTUBE)

A Study of TYRA-300 in Children With Achondroplasia: BEACH301

A Study of SmartFlow Magnetic Resonance (MR) Compatible Ventricular Cannula for Administering Eladocagene Exuparvovec to Pediatric Participants

Pediatric Safety Follow-up Study of Prior Treatment With Romosozumab for Osteogenesis Imperfecta

Psilocybin for Major Depressive Disorder (MDD)

First-In-Human Study of STX-721/PFL-721 in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring EGFR or HER2 Exon 20 Insertion Mutations

DemonsTTRate: A Global, Observational, Multicenter, Long-term Study of Patients With ATTR-CM in a Real-World Setting

Efficacy and Utility of Cxbladder Tests in Hematuria Patients

Intravitreal (IVT) Pozelimab for Geographic Atrophy (GA) in Adult Participants