Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Case Western Reserve University
The study is designed as a short pilot study which will assess safety and efficacy of high dose Vitamin D therapy in a heart failure population.
A 6 month randomized double blind placebo-controlled trial of 50,000 units of oral vitamin D3(cholecalciferol) weekly plus 800 calcium daily vs. weekly placebo plus 800 calcium alone in 64 heart failure (HF) patients \> 50 years old. This design was chosen over a cross-over design due to the long wash-out period for vitamin D.
Age
50–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
New York Heart Association (NYHA) class II-IV
Able to walk
Serum 25OHD level 37.5 ng/ml or less
Fully titrated on heart failure medications
You may not be if
Osteoporosis
Primary hyperparathyroidism or hypercalcemia.
Nephrolithiasis
Hemo or peritoneal dialysis and/or creatinine of \> 2.5
Current use of daily vitamin D greater than 400 IU, corticosteroids, parathyroid hormone (PTH), androgen or estrogen
Current illicit drug user or \> 3 alcoholic drinks a day
Metastatic or advanced cancer
Myocardial infarction in the preceding 6 months
Medications which can lower vitamin D levels or bioavailability
