Clinical Trials in Cleveland

Showing 5761-5780 of 19,775 trials

MIP Versus PCNL for Kidney Stone Disease

NCT04767919

The decision to use standard percutaneous nephrolithotomy (PCNL) versus mini-percutaneous nephrolithotomy (MIP) has been a subject of much debate in the urological community. The investigators propose a randomized controlled trial to compare the operative outcomes and complications of mini-percutaneous nephrolithotomy (mini-PCNL) versus standard PCNL for renal stones. The results of this study will help guide the decision making regarding these two procedures in the US population and provide further insight into the utility and safety of these procedures. A cost analysis will be performed, and it is hypothesized that the reusable components of the Storz MIP set will result in lower costs of the mini-PCNL procedure compared to standard PCNL.

Kidney Stone

University of California, San Diego75 participantsStarted Jan 2021

Phoenix, Arizona, United States • San Diego, California, United States • Cleveland, Ohio, United States +3 more locations

Active Not RecruitingPhase 3< 1 mile

Efficacy Against Oral Persistent Infection, Immunogenicity and Safety of the 9-valent Human Papillomavirus Vaccine (9vHPV) in Men Aged 20-45 Years (V503-049)

NCT04199689

The purpose of this study is to evaluate the efficacy, immunogenicity and safety of the 9vHPV vaccine in men 20 to 45 years of age. The primary hypothesis tested after the primary database lock is that administration of a 3-dose regimen of 9vHPV vaccine will reduce the incidence of human papillomavirus (HPV) 16/18/31/33/45/52/58-related oral persistent infection (6 months or longer) compared with placebo. There will also be an Extension Study to offer an opportunity to complete the 3 dose regimen of 9vHPV vaccine for participants who received placebo in the Base Study, or received less than 3 doses of 9vHPV vaccine in the Base Study.

Papillomavirus Infections

Merck Sharp & Dohme LLC6,033 participantsStarted Feb 2020

Northridge, California, United States • Rialto, California, United States • Simi Valley, California, United States +100 more locations

MIP Versus PCNL for Kidney Stone Disease

Efficacy Against Oral Persistent Infection, Immunogenicity and Safety of the 9-valent Human Papillomavirus Vaccine (9vHPV) in Men Aged 20-45 Years (V503-049)

Find Trials by Condition in Cleveland

A Study to Evaluate the Efficacy and Safety of Oral Zavegepant in Migraine Prevention

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Phase 2 Trial of Voyager V1 in Combination With Cemiplimab in Cancer Patients

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BURAN: Benralizumab on Airway Dynamics in Severe Eosinophilic Asthma Using Functional Respiratory Imaging

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Long-term Study of Semapimod (CNI-1493) for Treatment of Crohn's Disease

Kids FACE FEARS Comparative Effectiveness Research

Safety and Efficacy of BHV-3000 (Rimegepant) Orally Disintegrating Tablet for the Acute Treatment of Chronic Rhinosinusitis

Noninvasive Monitoring of Uterine Activity and Fetal Heart Rate

Efficacy and Safety Study of Narsoplimab in Pediatric Patients With High-Risk Hematopoietic Stem Cell Transplant TMA

Maximum Tolerated Dose, Safety, and Efficacy of Rhenium Nanoliposomes in Recurrent Glioma (ReSPECT)

Oxytocin and Brain Responses in Maternal Addiction

Walking and mHealth to Increase Participation in Parkinson Disease

Study to Investigate Hepatic Impairment on PK, Safety, Tolerability of Camizestrant in Post-Menopausal Female Subjects

Efficacy of Emotionally Focused Therapy Among Spanish Speaking Couples