Clinical Trials in Cleveland

Showing 5561-5580 of 15,050 trials

Study Using Negative Pressure to Reduce Apnea

NCT04861038

The objective of this study is to determine the safety and effectiveness of the aerSleep® II device for treatment of moderate to severe Obstructive Sleep Apnea (OSA) over 24 weeks of home use in spontaneously breathing adult subjects who are intolerant of Continuous Positive Airway Pressure (CPAP) therapy.

Sleep Apnea, ObstructiveApnea, Sleep

Sommetrics, Inc.900 participantsStarted Nov 2021

Tucson, Arizona, United States • Little Rock, Arkansas, United States • Los Angeles, California, United States +12 more locations

COMPLETEDPhase 1< 1 mile

BI 894999 First in Human Dose Finding Study in Advanced Malignancies

NCT02516553

This study is open to adults with different types of advanced cancer (solid tumours). The study is also open to patients with diffuse large B-cell lymphoma in whom previous treatment was not successful. In some countries, adolescents who are at least 15 years old and who are diagnosed with NUT carcinoma can also participate. No standard treatment exists for this rare and aggressive form of cancer. The purpose of this study is to find out the highest dose of BI 894999 that people can tolerate. BI 894999 is tested for the first time in humans. Participants take tablets once daily. The study also tests whether participants can tolerate BI 894999 better when taken continuously or with breaks in between. Participants can stay in the study as long as they benefit from the treatment and can tolerate it. The doctors also regularly check the general health of the participants.

NeoplasmsNUT Carcinoma

Boehringer Ingelheim174 participantsStarted Jul 2015

Boston, Massachusetts, United States • New York, New York, United States • Cleveland, Ohio, United States +13 more locations

Study Using Negative Pressure to Reduce Apnea

BI 894999 First in Human Dose Finding Study in Advanced Malignancies

Find Trials by Condition in Cleveland

Laser Ablation After Stereotactic Radiosurgery

Feasibility Study on LITT for Newly Diagnosed Glioblastoma

Laser Ablation in Stereotactic Neurosurgery (LAISE): NeuroBlate® Retrospective Registry

Open-Label Extension Study of Trofinetide for the Treatment of Girls and Women With Rett Syndrome

Allogeneic Heart Stem Cells to Achieve Myocardial Regeneration

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of BFKB8488A Compared With Placebo in Participants With Non-Alcoholic Steatohepatitis

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AG-946 in Healthy Volunteers and in Participants With Sickle Cell Disease

Geriatric Assessment Intervention for Reducing Toxicity in Older Patients With Advanced Cancer

Evaluation of Product Performance of a New Silicone Hydrogel Multifocal Contact Lens

Study to Evaluate the Safety and Pharmacokinetics of Efmarodocokin Alfa in Combination With Standard of Care in Participants Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

A SAD/MAD to Assess the Safety, PK/PD of FT-4202 in Healthy Volunteers and Sickle Cell Disease Patients

Phase I/IIa Study of H002 in NSCLC With Active EGFR Mutation

Financial Incentives, Randomization With Stepped Treatment Trial

Safety and Effectiveness Study of the Zenflow Spring System

Safety, Tolerability, and Pharmacokinetics of UX053 in Patients With Glycogen Storage Disease Type III (GSD III)

DWI in Assessing Treatment Response in Patients With Breast Cancer Receiving Neoadjuvant Chemotherapy

Longitudinal Observation of Insulin Requirements and Sensor Use in Pregnancy

Lyophilized Fecal Microbiome Transfer vs. Vancomycin Monotherapy for Primary Clostridioides Difficile Infection