Clinical Trials in Cleveland

Showing 5081-5100 of 19,775 trials

Neoadjuvant Radiosurgery for Resectable Brain Metastases: Phase I/II Study

NCT01891318

This Phase I/II trial studies the ability to stop brain metastases from coming back after treatment with radiosurgery followed by surgical resection. It will also evaluate the side effects of these combined treatments and help determine the best radiosurgery dose. Radiosurgery focuses the x-rays directly to the tumor and cause less damage to the normal tissue in the brain.

Tumors Metastatic to Brain

Case Comprehensive Cancer Center36 participantsStarted Jul 2013

Cleveland, Ohio, United States • Cleveland, Ohio, United States

COMPLETED< 1 mile

Misfolded Proteins in the Skin of People With Parkinson's Disease and Other Parkinsonism

NCT04518059

The purpose of this study is to determine whether identification of misfolded proteins in the skin will help to determine what sort of parkinsonism someone has. We seek to demonstrate whether someone has a synucleinopathy such as Parkinson's disease (PD), multiple system atrophy (MSA), or dementia with Lewy bodies(DLB), as opposed to a tauopathy such as progressive supranuclear palsy (PSP) or corticobasal degeneration (CBD) or no parkinsonism at all (control).

Parkinson DiseaseParkinsonismDementia With Lewy Bodies+3 more

University Hospitals Cleveland Medical Center184 participantsStarted Mar 2019

Cleveland, Ohio, United States • South Euclid, Ohio, United States

RECRUITINGNA< 1 mile

Distal Radius Interventions for Fracture Treatment

NCT05131685

This protocol describes a multicenter, prospective randomized superiority trial comparing functional outcomes between children treated with sedated reduction versus no formal reduction.

Fracture Distal Radius

Ann & Robert H Lurie Children's Hospital of Chicago334 participantsStarted Apr 2023

Phoenix, Arizona, United States • Los Angeles, California, United States • Los Angeles, California, United States +23 more locations

Neoadjuvant Radiosurgery for Resectable Brain Metastases: Phase I/II Study

Misfolded Proteins in the Skin of People With Parkinson's Disease and Other Parkinsonism

Distal Radius Interventions for Fracture Treatment

Find Trials by Condition in Cleveland

Vaginal Ecosystem and Network in the United States Study

A Phase III Trial of With Marizomib in Patients With Newly Diagnosed Glioblastoma

A Study to Investigate LYL797 in Adults With Solid Tumors

DAYBREAK: A Study of Setmelanotide in Participants With Specific Gene Variants in the Melanocortin-4 Receptor (MC4R) Pathway

A Study of EDP-938 in Non-hospitalized Adults With RSV Who Are at High Risk for Complications.

Pragmatic Randomised Trial of High Or Standard PHosphAte Targets in End-stage Kidney Disease (PHOSPHATE)

Study to Evaluate the Safety and Effectiveness of GP0116

Relapsing Forms of Multiple Sclerosis (RMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168) (GEMINI 1)

Comparison of Growth and Tolerance of Healthy Term Infants Fed Iron-Fortified Infant Formulas

A Study to Investigate LYL845 in Adults With Solid Tumors

A Study of Daratumumab and Dose-Adjusted EPOCH in Plasmablastic Lymphoma

A Study to Evaluate Guselkumab for the Treatment of Participants With New-onset or Relapsing Giant Cell Arteritis

Pertuzumab and Trastuzumab as Neoadjuvant Treatment in Patients With HER2-Positive Breast Cancer

Immune Checkpoint Inhibitor Nivolumab in People With Recurrent Select Rare CNS Cancers

Feasibility Study of the LVIS™ (Low-profile Visualized Intraluminal Support)Device

Study of Neoantigen-specific Adoptive T Cell Therapy for Newly Diagnosed MGMT Negative Glioblastoma Multiforme (GBM)

A Phase II Study Using Rituximab Plus Venetoclax in the Front Line Treatment of Marginal Zone Lymphoma