Clinical Trials in Cleveland

Showing 4821-4840 of 19,775 trials

Study of DKN-01 and Gemcitabine/Cisplatin in Patients With Carcinoma to Primary to the Intra- or Extra-Hepatic Biliary System or Gallbladder

NCT02375880

DKN-01 is a humanized monoclonal antibody (Mab) with neutralizing activity against Dkk-1 and is being developed as an anti-neoplastic agent. This study is designed to evaluate the safety, tolerability, pharmacokinetics, and anti-tumor activity of DKN-01 in combination with gemcitabine and cisplatin in patients with carcinoma primary to the intra- or exta-hepatic biliary system or gallbladder.

Carcinoma of Intrahepatic and Extra-hepatic Biliary SystemCarcinoma of GallbladderBile Duct Cancer+1 more

Leap Therapeutics, Inc.51 participantsStarted Jun 2015

Los Angeles, California, United States • New Haven, Connecticut, United States • Boston, Massachusetts, United States +6 more locations

Active Not RecruitingNA< 1 mile

Transorb™ Self-Gripping Resorbable Mesh in High-risk Subjects Undergoing Open Repair of Ventral Hernia

NCT06449378

The purpose of RECOVER is to evaluate the performance and safety of Transorb™ self-gripping resorbable mesh in high-risk subjects (at least one risk factor impairing wound healing) when used for reinforcement of abdominal wall soft tissues in procedures involving open extraperitoneal ventral hernia repair, in clean (US); and clean and clean-contaminated (Europe) surgical fields (Centers for Disease Control and Prevention (CDC) Classification I and II. Data from this study will primarily be used to support market approval and European post-market clinical follow-up needs. Secondarily, data will be used for product marketing, future product development, and to support market release and maintenance in global geographies.

HerniaHernia, VentralHernia, Abdominal+1 more

Medtronic - MITG163 participantsStarted Jul 2024

Evanston, Illinois, United States • Lexington, Kentucky, United States • Wilmington, North Carolina, United States +10 more locations

Study of DKN-01 and Gemcitabine/Cisplatin in Patients With Carcinoma to Primary to the Intra- or Extra-Hepatic Biliary System or Gallbladder

Transorb™ Self-Gripping Resorbable Mesh in High-risk Subjects Undergoing Open Repair of Ventral Hernia

Find Trials by Condition in Cleveland

Optimization of Adaptive Rowing Seating

Portico Next Generation Approval Study

Assessment of Coronary Microvascular Dysfunction After STEMI Using Continuous Saline Thermodilution

Study to Evaluate EP547 in Subjects With Cholestatic Pruritus Due to Primary Biliary Cholangitis or Primary Sclerosing Cholangitis

Study of SGR-3515 In Participants With Advanced Solid Tumors.

Study to Assess the Effects of PTC857 Treatment in Participants With Amyotrophic Lateral Sclerosis ALS

Topical Ruxolitinib Evaluation in Chronic Hand Eczema

A Study of Brigatinib in Participants With Anaplastic Lymphoma Kinase-Positive (ALK+), Advanced Non-Small-Cell Lung Cancer (NSCLC) Progressed on Alectinib or Ceritinib

A Study of Safety and Efficacy of MK-1986 (Tedizolid Phosphate) and Comparator in Participants From Birth to Less Than 12 Years of Age With Acute Bacterial Skin and Skin Structure Infections (MK-1986-018)

The NODE-202 Study (Study of Etripamil Nasal Spray in Pediatric Patients)

MGC018 With or Without MGA012 in Advanced Solid Tumors

Otitis Treatment With OtoSight™ - Modification of Antibiotic Treatment Intervention in Children

MYTHS - MYocarditis THerapy With Steroids

VentaProst Versus Conventionally-Administered Aerosolized Epoprostenol in Patients Undergoing Cardiac Surgery With CPB

Efficacy and Safety of TenoMiR in Lateral Epicondylitis

The LUCINDA Trial: LeUprolide Plus Cholinesterase Inhibition to Reduce Neurological Decline in Alzheimer's

Trial of LAVA-1207 in Patients With Therapy Refractory Metastatic Castration Resistant Prostate Cancer (mCRPC) Resistant Prostate Cancer

Pregnancy Exposure Registry for Vumerity (Diroximel Fumarate)