Pregnancy Exposure Registry for Vumerity (Diroximel Fumarate)

Inclusion Criteria

• •Participant must have a diagnosis of MS
• •Documentation that the participant was one of the following:
• •1. exposed to DRF at any time from 2 weeks after the first day of their LMP (i.e., conception date) up through any time during pregnancy. (If exact exposure dates are unknown, the reporter must be able to specify or estimate trimester of exposure).
• •2. unexposed to any DMT during pregnancy, defined as having never received DMT therapy; discontinued treatment with DRF at least 1 day before 2 weeks after the first day of their LMP (i.e., conception date); or discontinued a non Registry-specified MS DMT more than 5 times its half-life prior to 2 weeks after the first day of their LMP (i.e., conception date)
• •Participants with knowledge of the outcome of the pregnancy (e.g., pregnancy loss or live birth)