Clinical Trials in Cleveland

Showing 4121-4140 of 19,775 trials

Multi-Center Clean Air Randomized Controlled Trial in COPD

NCT06376994

This is a multi-center randomized, sham-controlled clinical trial to determine the effectiveness of an air cleaner intervention aimed at improving indoor air quality on reducing COPD exacerbation risk and improving quality of life, functional status, rescue medication use.

Chronic Obstructive Pulmonary Disease (COPD)

JHSPH Center for Clinical Trials770 participantsStarted May 2024

Birmingham, Alabama, United States • Los Angeles, California, United States • Iowa City, Iowa, United States +8 more locations

COMPLETEDPhase 2< 1 mile

A Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of SPR720 as Compared With Placebo for the Treatment of Participants With Mycobacterium Avium Complex (MAC) Pulmonary Disease

NCT05496374

The purpose of the study is to evaluate 1. The microbiological response and clinical efficacy of SPR720 compared with placebo in participants with nontuberculous mycobacteria pulmonary disease (NTM-PD). 2. The safety and tolerability of SPR720 in participants with NTM- PD 3. The pharmacokinetic (PK) of SPR719, active moiety, following orally (po) administered prodrug SPR720 in participants with NTM-PD.

Nontuberculous Mycobacterial Pulmonary Disease (NTM-PD)

Spero Therapeutics25 participantsStarted Dec 2022

Birmingham, Alabama, United States • Fresno, California, United States • Los Angeles, California, United States +25 more locations

Multi-Center Clean Air Randomized Controlled Trial in COPD

A Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of SPR720 as Compared With Placebo for the Treatment of Participants With Mycobacterium Avium Complex (MAC) Pulmonary Disease

Find Trials by Condition in Cleveland

A Study of BMS-813160 in Combination With Chemotherapy or Nivolumab in Participants With Advanced Solid Tumors

The Cancer of the Pancreas Screening-5 CAPS5)Study

The Use of Smart Glasses for Saphenous Nerve Adductor Canal Block

Pre-Op MRI on Margin Status for Transoral Robotic Surgery for HPV+ Tonsillar Squamous Cell Carcinoma

Study of Sitravatinib With or Without Other Anticancer Therapies Receiving Clinical Benefit From Parent Study

Dose Ranging Study of Amlitelimab in Adult Participants With Moderate-to-severe Asthma

Clinical Performance of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses

A Study of Subcutaneous Nivolumab Versus Intravenous Nivolumab in Participants With Previously Treated Clear Cell Renal Cell Carcinoma That is Advanced or Has Spread

Optilume PoST AppRoval Clinical Evaluation of Andrology ParaMeters

Study of a Novel Multicomponent Meningococcal Group B Vaccine When Given Alone or With Other Licensed Vaccines in Adults, Adolescents, Toddlers and Infants

A Study to Assess the Safety, Tolerability, and Effect on Disease Progression of BIIB105 in Participants With Amyotrophic Lateral Sclerosis (ALS) and Participants With the ALS Ataxin-2 (ATXN2) Genetic Mutation

A Sequential Phase 2/3 Study of APL2 in Patients With Focal Segmental Glomerulosclerosis

Safety, Tolerability and Efficacy Study of ARCT-032 in People With Cystic Fibrosis

Effects of Long-Duration Spaceflight on General and Spatial Cognition and Its Neural Basis

A Phase 2 Multicenter Study of High Dose Chemotherapy With Autologous Stem Cell Transplant Followed by Maintenance Therapy With Romidepsin for the Treatment of T Cell Non-Hodgkin Lymphoma

Extension of Phase 3 Gene Therapy for Painful Diabetic Neuropathy

Safety Study of Zinc Finger Nuclease CCR5-modified Hematopoietic Stem/Progenitor Cells in HIV-1 Infected Patients

Neuropsychological and Mental Outcomes of Operation Iraqi Freedom (OIF): A Longitudinal Cohort Study