Known or suspected impairment of immunologic function.
Acute medical illness with or without fever within the last 72 hours or an oral temperature ≥ 100.4°F (≥ 38.0°C) at the time of enrolment.
History of documented invasive meningococcal disease or previous meningococcal vaccination.
History of documented infection with Bordetella pertussis, Clostridium tetani, or Corynebacterium diphtheriae or vaccination with any tetanus, diphtheria or pertussis vaccine within the previous 5 years.
Received either immune globulin or other blood products within the last 3 months; or received injected or oral corticosteroids, or other immunomodulator therapy, within 6 weeks of the study vaccines. Individuals on a tapering dose schedule of oral steroids lasting \<7 days and individuals (e.g., asthmatics) on a short schedule of oral steroids lasting 3 to 4 days may be included in the trial as long as they have not received more than one course within the last 2 weeks prior to enrolment.
Received antibiotic therapy within the 72 hours prior to vaccination on Day 0.
Received any vaccine 28 days prior to the 1st study vaccination or scheduled to receive any vaccination during the course of the study.
Suspected or known hypersensitivity to either of the two study vaccines or their components.
Unavailable for the entire study period, or unable to attend the scheduled visits or to comply with the study procedures.
Enrolled in another clinical trial.
Diagnosed with any condition, which, in the opinion of the investigator, would pose a health risk to the subject or interfere with the evaluation of the vaccine.
For all females, a positive or equivocal urine pregnancy test at time of study vaccination.
Nursing mothers.
Clareo Health | Study of Menactra® in US Adolescents When Administered Concomitantly With Tdap Vaccine
