Clinical Trials in Chicago

Showing 6101-6120 of 15,574 trials

Trial of mFOLFOX6 + Trastuzumab + Avelumab in Gastric and Esophageal Adenocarcinomas

NCT03783936

The initial intent of the study was to be a multi-center single-arm open-label Simon's two-stage Phase II clinical trial of first-line mFOLFOX6 + trastuzumab + avelumab in metastatic HER2-amplified gastric and esophageal adenocarcinomas. Accrual will halt after completion of Stage I (enrollment of 18 patients). This decision is not due to safety issues. Subjects currently on treatment will continue until criteria as defined in the protocol is met.

Gastric AdenocarcinomaEsophageal AdenocarcinomaMetastasis+1 more

Ashwin Somasundaram18 participantsStarted Jan 2019

Duarte, California, United States • Atlanta, Georgia, United States • Chicago, Illinois, United States +4 more locations

COMPLETEDPhase 32.2 miles

Filgotinib in the Induction and Maintenance of Remission in Adults With Moderately to Severely Active Crohn's Disease

NCT02914561

The primary objectives of this study are to evaluate the safety and efficacy of filgotinib during induction and maintenance treatment of moderately to severely active Crohn's disease (CD) in participants who are biologic-naive and biologic-experienced. Participants who complete the study, or do not meet protocol response or remission criteria at Week 10 will have the option to enter a separate long-term extension (LTE) study (Study GS-US-419-3896).

Crohn's Disease

Galapagos NV1,372 participantsStarted Oct 2016

Dothan, Alabama, United States • Sun City, Arizona, United States • Coronado, California, United States +510 more locations

Trial of mFOLFOX6 + Trastuzumab + Avelumab in Gastric and Esophageal Adenocarcinomas

Filgotinib in the Induction and Maintenance of Remission in Adults With Moderately to Severely Active Crohn's Disease

Find Trials by Condition in Chicago

A Study of OCE-205 in Participants With Cirrhosis With Ascites Who Developed Hepatorenal Syndrome-Acute Kidney Injury

Sorafenib Tosylate Following a Liver Transplant in Treating Patients With Liver Cancer

Shockwave Medical Peripheral Lithoplasty System Study for PAD (Disrupt PAD III)

A Study to Evaluate SAGE-217 in Participants With Severe Postpartum Depression

Adjuvant Sequential & Concurrent CarboTaxol + Radiotherapy for High Risk Endometrial Cancer

Double-blind Study to Evaluate the Safety and Efficacy of Antroquinonol in Mild-Moderate COVID-19 Hospitalized Patients

Maximal Usage Pharmacokinetics and Safety of ARQ-151 in Children With Plaque Psoriasis (ARQ-151-215)

A Study in Healthy Volunteers to Compare the Pharmacokinetics of Sotorasib Administered as 1 or 2 Tablets

Study to Test the Efficacy and Safety of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adults With Drug-resistant Epilepsy

Sinusoidal Obstruction Syndrome for Stem Cell Transplant Patients Biomarker Study

Second-line Treatment of HIV-1 With Ritonavir Boosted Atazanavir or Darunavir With an Optimized NRTI Backbone

A Study of [225Ac]-FPI-1966 in Participants With Advanced Solid Tumours

A Clinical Study Evaluating Nivolumab-containing Treatments in Patients With Advanced Non-small Cell Lung Cancer After Failing Previous PD-1/(L)1 Therapy and Chemotherapy

Derazantinib in Subjects With FGFR2 Gene Fusion-, Mutation- or Amplification- Positive Inoperable or Advanced Intrahepatic Cholangiocarcinoma

Study of the CD40 Agonistic Monoclonal Antibody APX005M

The Canadian/US Integrative Oncology Study

Reveal LINQ Respiration Clinical Study

Survival Prolongation by Rationale Innovative Genomics