Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Northwestern University
With
National Parkinson Foundation
See above.
Age
Any age
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
1. Diagnosis of idiopathic PD as defined by the United Kingdom Parkinson's Disease Society Brain Bank Criteria
2. Hoehn and Yahr stage of 2 to 4 in the "on" state
3. Excessive daytime sleepiness as defined by the Epworth Sleepiness Scale (ESS) score of greater than or equal to 12 points
4. Stable PD medication regimen for at least 4 weeks prior to study screening
5. Willing and able to give written informed consent
You may not be if
1. Atypical parkinsonian syndromes
2. Significant sleep disordered breathing (defined as an apnea-hypopnea index \>15 events/hr of sleep on screening PSG)
3. Significant periodic limb movement disorder (defined as a PLM arousal index\>10 events/hr of sleep on screening PSG) and REM sleep behavior disorder (based on the presence of both clinical symptomatology as well as intermittent loss of REM atonia on screening PSG)
4. Cognitive impairment indicated by the mini-mental status examination (MMSE) score of less than 24
5. Presence of depression defined as the Beck Depression Inventory (BDI) score \>14
6. Untreated hallucinations or psychosis (drug-induced or spontaneous)
7. Use of hypno-sedative drugs for sleep or stimulants during the daytime
8. Use of antidepressants unless the patient has been on a stable dose for at least three months
9. Visual abnormalities that may interfere with light therapy, such as significant cataracts, narrow angle glaucoma or blindness
10. Travel through 2 time zones within 90 days prior to study screening
