Clinical Trials in Boston

Showing 1881-1900 of 17,836 trials

Ultrasound Guided Femoral Nerve Block

NCT02381717

The goal of the study is to evaluate whether pain control achieved by Ultrasound Guided Femoral Nerve Blockade (USFNB) is equal in efficacy to standard pain management practice of parenteral injection of opioid pain medication in patients presenting to the emergency department (ED) with hip fracture.

Hip Fracture

Beth Israel Deaconess Medical Center44 participantsStarted Aug 2015

Boston, Massachusetts, United States • Worcester, Massachusetts, United States

RECRUITINGPhase 3< 1 mile

A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer

NCT05894239

This study will evaluate the efficacy and safety of inavolisib in combination with Phesgo (pertuzumab, trastuzumab, and rHuPH20 injection for subcutaneous use) compared with placebo in combination with Phesgo, as maintenance therapy, after induction therapy in participants with previously untreated HER2-positive advanced breast cancer (ABC).

Metastatic Breast Cancer

Hoffmann-La Roche230 participantsStarted Sep 2023

Gilbert, Arizona, United States • Burbank, California, United States • Corona, California, United States +184 more locations

Ultrasound Guided Femoral Nerve Block

A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer

Find Trials by Condition in Boston

Multidisciplinary Intervention for Adults With Chronic Graft-versus-host Disease

A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic oHCM

Comparing PFO Outcomes of the Occlutech Flex II PFO Occluder to Standard of Care PFO Occlusion

Reference Range Study for the Quantra System With the QPlus Cartridge in Pediatric Patients

Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous Disease

Study of Olaparib Plus Pembrolizumab Versus Chemotherapy Plus Pembrolizumab After Induction With First-Line Chemotherapy Plus Pembrolizumab in Triple Negative Breast Cancer (TNBC) (MK-7339-009/KEYLYNK-009)

Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors

DFF332 as a Single Agent and in Combination With Everolimus & Immuno-Oncology Agents in Advanced/Relapsed Renal Cancer & Other Malignancies

Pilot Study of Neuromodulation for Enhancement of Emotion Regulation in Bipolar Mood Disorders

A 2-year Study of EYP-1901 in Subjects With Wet Age Related Macular Degeneration (wAMD) (LUCIA) Primary Efficacy Will be Determined at Week 56

First-in-Human (FIH) Trial in Patients With Relapsed, Progressive or Refractory B-Cell Lymphoma

A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (COPD)

A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma

Open-label Study of BBO-8520 in Adult Subjects With KRASG12C Non-small Cell Lung Cancer

A Study to Investigate ALE.P02 as Monotherapy in Adult Patients With Selected CLDN1+ Solid Tumors

A Research Study to Evaluate the Effects of a New Oral Medicine Called Cenerimod in Adults With Systemic Lupus Erythematosus

Double-J PLUS Postmarket Registry Study