Clinical Trials in Boston

Showing 1721-1740 of 8,503 trials

Radiation, Immunotherapy and PARP Inhibitor in Triple Negative Breast Cancer

NCT04837209

This research study is looking to see whether the combination of Dostarlimab and Niraparib plus Radiation Therapy (RT) is safe and effective in participants with metastatic triple negative breast cancer. The names of the study treatment involved in this study are: * Dostarlimab * Niraparib * Radiation Therapy (RT), which is given per standard of care.

Breast CancerTriple Negative Breast Cancer

Massachusetts General Hospital32 participantsStarted Jul 2021

Washington D.C., District of Columbia, United States • Boston, Massachusetts, United States • Durham, North Carolina, United States +1 more locations

RECRUITINGPhase 2< 1 mile

Selinexor (KPT-330) in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)

NCT02227251

A multicenter, open-label Phase 2b study of selinexor (KPT-330) in participants with relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL) who have no therapeutic options of demonstrated clinical benefit.

Diffuse Large B-cell Lymphoma

Karyopharm Therapeutics Inc244 participantsStarted Nov 2014

Tucson, Arizona, United States • San Francisco, California, United States • Santa Monica, California, United States +173 more locations

Radiation, Immunotherapy and PARP Inhibitor in Triple Negative Breast Cancer

Selinexor (KPT-330) in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)

Find Trials by Condition in Boston

Study of TPX-0022 in Patients With Advanced NSCLC, Gastric Cancer or Solid Tumors Harboring Genetic Alterations in MET

Evaluation of Efficacy and Safety of VX-548 for Painful Lumbosacral Radiculopathy (PLSR)

Losartan and Nivolumab in Combination With FOLFIRINOX and SBRT in Localized Pancreatic Cancer

HIP Fracture Accelerated Surgical TreaTment And Care tracK 2 Trial

A Study to Investigate the Safety and Efficacy of KER-012 in Combination With Background Therapy in Adult Participants With Pulmonary Arterial Hypertension (PAH) (TROPOS Study).

Safety, Tolerability and Efficacy of AntiBKV as Treatment of BKV Infection in Kidney Transplant Recipients

OP5-005 Using Omnipod 5 in Adults With Type 2

CERAMENT™| Bone Void Filler Device Registry

A Registry for Participants With Chronic Hypoparathyroidism

Targeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal Dystrophy

Carboplatin +/- Nivolumab in Metastatic Triple Negative Breast Cancer

Effects of tDCS and tUS on Pain Perception in OA of the Knee

Role of Parent Interpretation Bias in the Transmission of Anxiety to Children

An Efficacy, Safety, and Tolerability Study of VRDN-003 in Participants With Active Thyroid Eye Disease (TED)

Phase 1b Safety Study of Xevinapant, Weekly Cisplatin, and RT in Participants With Unresected LA SCCHN (HyperlynX)

A Phase 1 Study of of Anti-CD7 Allogeneic CAR-T Cell Therapy (WU-CART-007) in Patients With Relapsed or Refractory T-ALL/LBL

Proof-of-concept Study for SAR441344 (Frexalimab) in Relapsing Multiple Sclerosis

A Clinical Study to Evaluate the Use of a Cryopreserved Formulation of OTL-103 in Subjects With Wiskott-Aldrich Syndrome