Clinical Trials in Boston

Showing 12701-12720 of 15,299 trials

Noninvasive Assessment of Neuromuscular Disease Using Electrical Impedance Myography

NCT01803386

The purpose of this protocol is to test a new Electrical Impedance Myography (EIM) device and study its reliability and ability to differentiate ALS patients from healthy controls.

Amyotrophic Lateral Sclerosis (ALS)

Skulpt, Inc.20 participantsStarted Jan 2013

Boston, Massachusetts, United States

TERMINATED< 1 mile

PET/CT to Predict Response to Infliximab Therapy in Patients With Crohn's Disease

NCT01759017

The costs and potential complications (side effects) of therapies currently used to treat Crohn's disease could be reduced if a non-invasive test existed that determined which therapies benefit patients and which do not. A non-invasive test is a test that does not involve cutting or entering the skin. Currently, once therapies are prescribed, doctors rely solely on clinical parameters to gauge whether the therapies are helpful. This includes evaluation of overall general well-being, abdominal pain, and number of liquid stools per day. There is no established and reliable non-invasive test that can predict whether a person is responding to therapy early in the course of treatment when these evaluations may be inconclusive. During this research study we will look for changes in sugar metabolism on low-dose PET/CT before and 2 weeks after the first infusion of infliximab therapy. This is to find out if these changes can predict clinical response and steroid-free remission at two, six and 12 months, in patients with Crohn's disease.

Crohn's Disease

Brigham and Women's Hospital8 participantsStarted Dec 2012

Boston, Massachusetts, United States

COMPLETEDPhase 1< 1 mile

Safety, Tolerability and Pharmacokinetics of Single Dose Intravenous Moxifloxacin in Pediatric Patients

NCT01049022

The purpose of this study is to describe the pharmacokinetics of moxifloxacin in children to see what the best dose should be for children in the future. Pharmacokinetics is to see how the body absorbs, distributes, breaks down and gets rid of the study drug. The pharmacokinetics of certain drugs may be altered in children due to developmental differences in various organ functions responsible for drug elimination, as well as in general distribution characteristics. The safety of moxifloxacin in children with infections will also be looked at. Results from this study will be used to guide dosing strategies of the larger clinical trial planned for children

Infections

Bayer31 participantsStarted May 2010

Little Rock, Arkansas, United States • Orange, California, United States • San Diego, California, United States +8 more locations

Noninvasive Assessment of Neuromuscular Disease Using Electrical Impedance Myography

PET/CT to Predict Response to Infliximab Therapy in Patients With Crohn's Disease

Safety, Tolerability and Pharmacokinetics of Single Dose Intravenous Moxifloxacin in Pediatric Patients

Find Trials by Condition in Boston

Mobile Motivation for Health Promotion Among Adolescents

Improving Safety By Computerizing Outpatient Prescribing

Accuracy of the Pima™ CD4 Test for Enumeration of CD4+ T-Cell Counts

A Retrospective Chart Review of Patients Treated With Ocriplasmin for Symptomatic VMA

Rollover Study of VX-770 in Cystic Fibrosis Subjects

BRAIN (Biomarker Rapid Assessment of Ischemic iNjury)

Study of PXD101 Alone and in Combination With 5-Fluorouracil (5-FU) in Patients With Advanced Solid Tumors

A 16 Weeks Study on Efficacy and Safety of Two Doses of Empagliflozin (BI 10773) (Once Daily Versus Twice Daily) in Patients With Type 2 Diabetes Mellitus and Preexisting Metformin Therapy

A Study to Compare Tenofovir DF Versus the Combination of Emtricitabine Plus Tenofovir DF for the Treatment of Chronic Hepatitis B in Patients With Normal Alanine Aminotransferase (ALT)

Open Label Controlled Trial of Eculizumab in Adult Patients With Plasma Therapy-Resistant aHUS

Open Label Controlled Trial of Eculizumab in Adolescent Patients With Plasma Therapy-Resistant aHUS

Clinical Trial of PXD101 in Patients With Advanced Multiple Myeloma

Study to Evaluate the Safety, Tolerability and Efficacy of FOLFOX + CT-011 Versus FOLFOX Alone

Study to Evaluate Hemodynamic Effect of Different Loading Doses of Precedex in Post-surgical Intensive Care Unit (ICU) Patients

Screening for Occult Malignancy in Patients With Idiopathic Venous Thromboembolism

Open-label Study of Levetiracetam Intravenous Infusion in Children (1 Month-4 Years Old) With Epilepsy

Sarizotan in the Treatment of Neuroleptic-induced Tardive Dyskinesia