Clinical Trials in Boston

Showing 12661-12680 of 15,299 trials

Lapatinib Ditosylate and Akt Inhibitor MK2206 in Treating Women With Metastatic Breast Cancer

NCT01281163

This phase I trial studies the side effects and the best dose of lapatinib ditosylate and Akt inhibitor MK2206 in treating women with metastatic breast cancer. Lapatinib ditosylate and Akt inhibitor MK2206 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Estrogen Receptor NegativeEstrogen Receptor PositiveHER2/Neu Positive+4 more

National Cancer Institute (NCI)4 participantsStarted Jan 2011

New Haven, Connecticut, United States • Boston, Massachusetts, United States • Ann Arbor, Michigan, United States +2 more locations

COMPLETEDPhase 2< 1 mile

Sunitinib Malate in Treating Younger Patients With Recurrent, Refractory, or Progressive Malignant Glioma or Ependymoma

NCT01462695

This phase II trial studies how well sunitinib malate works in treating younger patients with recurrent, refractory, or progressive malignant glioma or ependymoma. Sunitinib malate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Childhood Cerebellar Anaplastic AstrocytomaChildhood Cerebral Anaplastic AstrocytomaChildhood Cerebral Astrocytoma+8 more

National Cancer Institute (NCI)30 participantsStarted Jan 2012

Birmingham, Alabama, United States • Birmingham, Alabama, United States • Little Rock, Arkansas, United States +93 more locations

Lapatinib Ditosylate and Akt Inhibitor MK2206 in Treating Women With Metastatic Breast Cancer

Sunitinib Malate in Treating Younger Patients With Recurrent, Refractory, or Progressive Malignant Glioma or Ependymoma

Find Trials by Condition in Boston

A Study of Fresolimumab in Patients With Steroid-Resistant Primary Focal Segmental Glomerulosclerosis (FSGS)

Short-Term vs. Long-Term Valganciclovir Therapy for Symptomatic Congenital CMV Infections

fFN Clinical Evaluation in Asymptomatic Women at High Risk for Preterm Birth

S0618 E7389 in Treating Patients With Metastatic or Recurrent Head and Neck Cancer

AIN457 Regimen Finding Study in Patients With Moderate to Severe Psoriasis

Testing Strategies for Increasing Exercise

Effect of Azithromycin on Lung Function in 6-18 Year-olds With Cystic Fibrosis (CF) Not Infected With P. Aeruginosa

Familial Intracranial Aneurysm Study II

Safety Study for the Treatment of Abdominal Aortic Aneurysms

Concurrent Treatment for Depressed Parents and DepressedAdolescents

Gadobutrol Enhanced MRA of the Renal Arteries

Panitumumab and Gemcitabine in Relapsed Ovarian Cancer

Improving the Quality of Cardiopulmonary Resuscitation (CPR) During Pediatric Cardiac Arrest

Extension to CQTI571A2102 to Evaluate Long-term Safety, Tolerability and Efficacy of Imatinib in Severe Pulmonary Arterial Hypertension (PAH)

Combination of Orally Inhaled BI1744CL/Tiotropium Bromide in Patients With Chronic Obstructive Pulmonary Disease ( COPD)

A Study of Avastin (Bevacizumab) in Combination With Herceptin (Trastuzumab)/Docetaxel in Patients With HER2 Positive Metastatic Breast Cancer.

Efficacy and Safety of 4 Weeks of Treatment With Orally Inhaled BI1744/Tiotropium Bromide in Patients With Chronic Obstructive Pulmonary Disease (COPD)

A Study to Evaluate the Safety and Efficacy of Adding Enfuvirtide to Oral Highly Active Antiretroviral Therapy (HAART) in Human Immunodeficiency Virus (HIV) Patients With Prior Treatment Experience