Clinical Trials in Boston

Showing 1201-1220 of 8,503 trials

The HistoSonics Edison™ System for Treatment of Primary Solid Renal Tumors Using Histotripsy (#HOPE4KIDNEY)

NCT05820087

The purpose of this trial is to evaluate the effectiveness and safety of the HistoSonics Edison System for the destruction of kidney tissue by treating primary solid renal tumors.

Renal CancerTumor, SolidKidney Cancer+2 more

HistoSonics, Inc.67 participantsStarted Jan 2024

Los Angeles, California, United States • Los Angeles, California, United States • Mission Viejo, California, United States +12 more locations

Active Not RecruitingPhase 1< 1 mile

A Study of AMG 355 Alone and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors

NCT06131398

The primary objectives of this study are to: * Evaluate the safety and tolerability of AMG 355 as monotherapy and in combination with pembrolizumab in participants with advanced solid tumors * Determine the recommended phase 2 dose and the maximum tolerated dose for AMG 355 as monotherapy and in combination with pembrolizumab in participants with advanced solid tumors.

Advanced Solid Tumors

Amgen77 participantsStarted Mar 2024

Duarte, California, United States • Merriam, Kansas, United States • Boston, Massachusetts, United States +22 more locations

The HistoSonics Edison™ System for Treatment of Primary Solid Renal Tumors Using Histotripsy (#HOPE4KIDNEY)

A Study of AMG 355 Alone and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors

Find Trials by Condition in Boston

A Study to Investigate Multiple Sclerosis Relapse Prevention With mRNA-1195 Compared With Placebo in Participants Aged 18 to ≤55 Years

ExCrossV Multi Site Trial for Vascularized High Risk Keratoplasty

Strategic Help With Immunoglobulin to Enhance Protect Against Late Disease (CMV)

Combined Cortical/Subcortical Recording and Stimulation as a Circuit-Oriented Treatment for Obsessive-Compulsive Disorder

A Study to Test if Fremanezumab is Effective in Preventing Chronic Migraine in Participants 6 to 17 Years of Age

A Trial to Assess the Safety and Efficacy of Subjects With Dry Eye Disease

FORCE-TJR: Improving Orthopedic Outcomes Through a National TJR Registry

Addressing Weight Bias Internalization to Improve Adolescent Weight Management Outcomes: Open Trial

A Phase 3, Randomized, Double-blind Study for Patients With Invasive Candidiasis Treated With IV Echinocandin Followed by Either Oral Ibrexafungerp or Oral Fluconazole

NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

A Study Comparing Abelacimab to Dalteparin in the Treatment of Gastrointestinal/Genitourinary Cancer and Associated VTE

A Study of Vericiguat (MK-1242) in Participants With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF) (MK-1242-035)

Basket Study of Tucatinib and Trastuzumab in Solid Tumors With HER2 Alterations

Phase 3 Study of Pyrotinib Versus Docetaxel in Patients With Advanced Non-squamous NSCLC Harboring a HER2 Exon 20 Mutation Who Failed Platinum Based Chemotherapy

Phase I/II Study of [225Ac]Ac-PSMA-R2 in PSMA-positive Prostate Cancer, With/Without Prior 177Lu-PSMA RLT

First-Time-in-Human Study of GSK4381562 in Participants With Advanced Solid Tumors

HDClarity: a Multi-site Cerebrospinal Fluid Collection Initiative to Facilitate Therapeutic Development for Huntington's Disease

Pinnacle RSA Study