Clinical Trials in Boston

Showing 11821-11840 of 15,299 trials

A Novel Unidirectional Face Mask During NPPV in COPD Patients

NCT00972868

The purpose of this study is to determine the feasibility, safety and efficacy of a unidirectional breathing mask (breathe in through the nose and out through the mouth or breathe in through the mouth and out through the nose) in COPD patients with breathing difficulties requiring noninvasive positive pressure ventilation (NPPV).

Chronic Obstructive Pulmonary Disease

Massachusetts General HospitalStarted Mar 2011

Boston, Massachusetts, United States

COMPLETEDPhase 4< 1 mile

An Open-Label Study of Naltrexone in Adults With Attention Deficit Hyperactivity Disorder.

NCT01873729

The primary aim of this study is to assess whether naltrexone as a monotherapy is effective in treating Attention Deficit Hyperactivity Disorder (ADHD) in adults. Medications that increase dopamine are often effective in treating ADHD in adults. Since naltrexone is a kappa opioid receptor antagonist, it increases dopamine in the brain. We predict that naltrexone as a monotherapy will be effective for ADHD symptoms in adults with ADHD.

Attention Deficit Hyperactivity Disorder

Massachusetts General Hospital3 participantsStarted Nov 2013

Boston, Massachusetts, United States

WITHDRAWN< 1 mile

Proline Metabolism in Severely Burned Patients: Effect of Modulated Parenteral Feeding

NCT00216983

The overall purpose of the study is to evaluate the effect of depleting proline supply in the nutritional support regimen on proline metabolism in the burn patients, this includes the rate of proline oxidation after burn injury, the rate of proline de novo synthesis from its immediate precursors glutamate and ornithine. The specific aims of the proposed study are: 1) to determine the kinetic status of proline metabolism and whole body proline balance under the following nutritional states: (a) "fasting; (b) regular total parenteral nutrition (TPN); (c)TPN with isonitrogenous depletion of proline, glutamate and ornithine metabolism under nutritional conditions studied in specific aim 1) above.

Burns

Massachusetts General HospitalStarted Sep 1997

Boston, Massachusetts, United States

A Novel Unidirectional Face Mask During NPPV in COPD Patients

An Open-Label Study of Naltrexone in Adults With Attention Deficit Hyperactivity Disorder.

Proline Metabolism in Severely Burned Patients: Effect of Modulated Parenteral Feeding

Find Trials by Condition in Boston

Efficacy of NicVAX in Smokers Who Want to Quit Smoking

Use of Activated Recombinant Human Factor VII in Cardiac Surgery

Efficacy of NovoSeven® in Bleeding Prophylaxis in Hemophilia

Trial of NovoSeven® in Haemophilia - Joint Bleeds

Cardiac Hemodynamics in Overlap Syndrome (COPD With Obstructive Sleep Apnea)

Treatment Efficacy for Drug Abuse and AIDS Prevention - 2

Job-Seekers Training for Patients With Drug Dependence - 1

Preventing Depression in Methadone Maintenance Patients Receiving Hepatitis C Treatment - 1

Post Acute Coronary Event Smoking Study

Percutaneous Cryoablation in Treating Patients With Painful Bone Metastases

HIV and HCV Intervention In Drug Treatment Settings - 1

GAPP 2 Survey: Global Attitudes of Patients and Physicians in Insulin Therapy for Type 2 Diabetes Mellitus

Use Of SB424323 With Aspirin In Non-Valvular Atrial Fibrillation In Patients At A Low Or Intermediate Risk For Stroke

Safety and Preliminary Efficacy of Recombinant Activated Factor VII in Subjects With Traumatic Brain Injury

A Study of Intra-thrombus Plasmin (Human) In Acute Peripheral Arterial Occlusion

Efficacy, Safety, and Tolerability of Brexpiprazole (OPC-34712) as Maintenance Treatment in Adults With Schizophrenia

Follow-up Study to Assess Visual Function in Subset of Patients Who Have Previously Participated in the TG-MV-006 and TG-MV-007 Ocriplasmin Studies