Clinical Trials in Boston

Showing 11081-11100 of 15,299 trials

Immunosuppression in Amyotrophic Lateral Sclerosis (ALS)

NCT01884571

This is a multicenter, 15-month study evaluating the effect of immunosuppression treatment on the rate of change on the ALS Functional Rating Scale (Revised) (ALSFRS-R) score in up to 33 subjects with Amyotrophic Lateral Sclerosis (ALS).

Amyotrophic Lateral Sclerosis (ALS)

Emory University31 participantsStarted Oct 2013

Atlanta, Georgia, United States • Boston, Massachusetts, United States • Worcester, Massachusetts, United States

COMPLETEDPhase 2< 1 mile

S0601 Rituximab, Combination Chemotherapy, and Bortezomib Followed by Bortezomib Alone in Treating Patients With Newly Diagnosed Mantle Cell Lymphoma

NCT00376961

RATIONALE: Monoclonal antibodies, such as rituximab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and help kill them or carry cancer-killing substances to them. Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving rituximab together with combination chemotherapy and bortezomib may kill more cancer cells. Giving bortezomib as maintenance therapy may keep the cancer from progressing. PURPOSE: This phase II trial is studying how well giving rituximab together with combination chemotherapy and bortezomib followed by bortezomib alone works in treating patients with newly diagnosed mantle cell lymphoma.

Lymphoma

SWOG Cancer Research Network68 participantsStarted Aug 2006

Anchorage, Alaska, United States • Anchorage, Alaska, United States • Tucson, Arizona, United States +144 more locations

Immunosuppression in Amyotrophic Lateral Sclerosis (ALS)

S0601 Rituximab, Combination Chemotherapy, and Bortezomib Followed by Bortezomib Alone in Treating Patients With Newly Diagnosed Mantle Cell Lymphoma

Find Trials by Condition in Boston

A Pilot Study of Inosine in Amyotrophic Lateral Sclerosis (ALS)

A Study to Evaluate the Safety and Tolerability of Valproic Acid in Trauma Patients(Part 2)

Impact of Music on Satisfaction, Anxiety, and Hemodynamics During Spinal Anesthesia for Cesarean Delivery

Dose-Ranging Study In Subjects With Type 2 Diabetes Mellitus Who Are Treatment-Naive

Evaluation of the GORE Conformable TAG® Thoracic Endoprosthesis for Treatment of Acute Complicated Type B Aortic Dissection

Rituximab for ANCA-associated Vasculitis (RAVE) Long-Term Follow-Up Study

Phase 2 Dose-finding Study to Evaluate the Effects of BA058 in the Treatment of Postmenopausal Women With Osteoporosis

Ablation of Intestinal Metaplasia Containing Dysplasia

Study of Terlipressin Versus Placebo to Treat Hepatorenal Syndrome Type 1

Minimally Invasive Closure of Umbilical Hernias

Six Month Study to Evaluate the Safety and Effectiveness of the Intranasal Lacrimal Neurostimulator

A Study Comparing Cardiovascular Effects of Ticagrelor and Clopidogrel in Patients With Peripheral Artery Disease

A Clinical Trial Testing The Efficacy Of Crizotinib Versus Standard Chemotherapy Pemetrexed Plus Cisplatin Or Carboplatin In Patients With ALK Positive Non Squamous Cancer Of The Lung

A Clinical Trial to Evaluate the Efficacy and Safety of Testosterone Gel

Study Evaluating Inotuzumab Ozogamicin (CMC-544) In Indolent Non-Hodgkins Lymphoma

Comparison of Liraglutide Versus Placebo in Weight Loss Maintenance in Obese Subjects: SCALE - Maintenance

Phase 1 Study of ATR-101 in Subjects With Advanced Adrenocortical Carcinoma

A Study of EDP-305 in Subjects With Mild and Moderate Hepatic Impairment Compared With Normal Healthy Volunteers