Clinical Trials in Boston

Showing 10441-10460 of 15,299 trials

A Study of Effects of Age and Hyperkyphosis on Spine Motion and Loading

NCT03008902

We are studying how spine movement changes with age, and when people have vertebral fractures (cracks in the bones of the spine) or hyperkyphosis (a forward stooped posture).

KyphosisVertebral Fracture

Beth Israel Deaconess Medical Center41 participantsStarted Apr 2017

Boston, Massachusetts, United States

WITHDRAWNPhase 2< 1 mile

Nivolumab or Expectant Observation Following Ipilimumab, Nivolumab, and Surgery in Treating Patients With High Risk Localized, Locoregionally Advanced, or Recurrent Mucosal Melanoma

NCT03220009

This randomized phase II trial studies how well nivolumab or expectant observation following ipilimumab, nivolumab, and surgery work in treating patients with high-risk mucosal melanoma that is restricted to the site of origin without evidence of spread, has spread to a local and regional area of the body, or has come back. Monoclonal antibodies, such as nivolumab and ipilimumab, may interfere with the ability of tumor cells to grow and spread. Sometimes the mucosal melanoma may not need more treatment until it progresses. In this case, observation may be sufficient. It is not known if nivolumab or expectant observation following ipilimumab, nivolumab, and surgery may be better in treating patients with mucosal melanoma.

Cervical CarcinomaEsophageal CarcinomaMucosal Melanoma+14 more

National Cancer Institute (NCI)Started Nov 2017

Boston, Massachusetts, United States

A Study of Effects of Age and Hyperkyphosis on Spine Motion and Loading

Nivolumab or Expectant Observation Following Ipilimumab, Nivolumab, and Surgery in Treating Patients With High Risk Localized, Locoregionally Advanced, or Recurrent Mucosal Melanoma

Find Trials by Condition in Boston

CRUSH STUDY: Calculating Readmission Risk by Ultrasound for Heart Failure Failure Study

The PARTNER II Trial: Placement of AoRTic TraNscathetER Valves - PII B

Phase II Combination Steroid and Anti-VEGF for Persistent DME

Free Fatty Acids and Vascular Function in Subjects With Diabetes

Procedures for Improving the Mucosa Around Implants

A Dose-ranging Study With Brivaracetam in Patients From 16 to 65 Years With Refractory Partial Onset Seizures.

Multicenter Continuous Peripheral Nerve Block Surveillance Study

Assessing Tobacco Product Choice When the Cost of Menthol Cigarettes Increases

Paclitaxel and Carboplatin in Treating Patients With Persistent or Recurrent Stage III or Stage IV Uterine Cancer

Assessing Fitting Guides in Alcon Multifocal Contact Lenses

A Pilot Study to Evaluate the Use of Smart Adherence Technology to Measure Lumacaftor/Ivacaftor Adherence in CF Subjects Homozygous for the F508del CFTR Mutation

Study of Epratuzumab Versus Placebo in Subjects With Moderate to Severe General Systemic Lupus Erythematosus

Plant Cell Expressed Recombinant Human Glucocerebrosidase Extension Trial

Open-label Long-term Safety Study of AT1001 (Migalastat Hydrochloride) in Participants With Fabry Disease Who Have Completed a Previous AT1001 Study

Efficacy, Pharmacokinetics, and Safety of Presatovir in Hospitalized Adults With Respiratory Syncytial Virus (RSV) Infection

A Long-term Safety Study of ALKS 9072 (Also Known as ALKS 9070)

Study Comparing Blood Levels of ReFacto and Advante in Hemophilia A

Gastric Electrical Stimulation (GES) for the Treatment of Obesity