Clinical Trials in Boston

Showing 1021-1040 of 17,836 trials

A Global Study of the PETAL Consortium

NCT06067347

The goal of this observational study is to correlate molecular alterations with outcomes including overall survival (OS), progression-free survival (PFS), response rates for patients with a new diagnosis, primary refractory or relapse, of mature T-cell and NK-cell neoplasms (TNKL). We hypothesize that machine learning can be leveraged to uncover distinct genetic vulnerabilities that underlie treatment response and resistance for patients with TNKL, thus moving towards personalized treatment solutions.

T-Cell and NK-Cell Neoplasm

Massachusetts General Hospital1,200 participantsStarted Jan 2024

Duarte, California, United States • Denver, Colorado, United States • Tampa, Florida, United States +11 more locations

RECRUITINGPhase 1/2< 1 mile

A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy

NCT06388707

This will be a prospective, open-label, single-arm, multi-center, pilot study to evaluate the safety, tolerability, and preliminary efficacy of low-intensity focused ultrasound (LIFU) neuromodulation using NaviFUS System in patients with drug-resistant unilateral or bilateral temporal lobe epilepsy (DR-TLE).

Drug Resistant EpilepsyEpilepsySeizures, Focal+2 more

NaviFUS Corporation8 participantsStarted Sep 2024

Palo Alto, California, United States • Boston, Massachusetts, United States • Charlottesville, Virginia, United States

A Global Study of the PETAL Consortium

A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy

Find Trials by Condition in Boston

A Study of Dazostinag as Single Agent and Dazostinag in Combination With Pembrolizumab in Adults With Advanced or Metastatic Solid Tumors

Rituximab/Bendamustine + Rituximab/Cytarabine for Mantle Cell Lymphoma

Avecure Flexible Microwave Ablation Probe For Lung Nodules

A Randomized Clinical Trial of Ex Vivo Corneal Cross-Linking of Donor Keratoplasty Tissue for Keratoconus Used for Keratoplasty in Keratoconus Patients

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

An Empowering Parent Training Intervention to Increase Physical Activity in Preschool Aged Children With Autism

Dance Study for Post-surgical Pain in Breast Cancer Survivors

Safety and Efficacy of Endovascular Treatment of Intracranial Aneurysms With Surpass Elite With GUARDian Flow Diverter (GUARD)

Hyperangulated Versus Standard Geometry Laryngoscope Blade Trial

A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin, SGLT2 Inhibitor or Both

Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

Understanding Needs of Older Patients Prior to Starting Cancer Treatment

Surgical Thromboprophylaxis Practices in Oncology Patients Within the NCORP Network, STOP-VTE Study

A Study to Compare Different Doses of RO7795081 With a Placebo or Semaglutide in People With Type 2 Diabetes

Study of GS-1427 in Participants With Moderately to Severely Active Ulcerative Colitis

A Study About the Long-Term Safety of TAK-881 in People With Primary Immunodeficiency Diseases

IO102-IO103 in Combination With Pembrolizumab as First-line Treatment for Patients With Metastatic NSCLC, SCCHN, or mUBC

The EVARREST® Pediatric Mild or Moderate Liver and Soft Tissue Bleeding Study