Clinical Trials in Boston

Showing 10301-10320 of 15,299 trials

Akt Inhibitor MK2206 in Treating Patients With Advanced Breast Cancer

NCT01277757

This phase II trial studies how well Akt inhibitor MK2206 works in treating patients with breast cancer cancer that has spread to other places in the body and usually cannot be cured or controlled with treatment. Akt inhibitor MK2206 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Recurrent Breast CarcinomaStage IIIB Breast CancerStage IIIC Breast Cancer+1 more

National Cancer Institute (NCI)30 participantsStarted Mar 2011

Boston, Massachusetts, United States • Boston, Massachusetts, United States • New York, New York, United States +2 more locations

COMPLETEDPhase 3< 1 mile

Cytarabine and Daunorubicin Hydrochloride or Idarubicin and Cytarabine With or Without Vorinostat in Treating Younger Patients With Previously Untreated Acute Myeloid Leukemia

NCT01802333

This randomized phase III trial studies cytarabine and daunorubicin hydrochloride or idarubicin and cytarabine with or without vorinostat to see how well they work in treating younger patients with previously untreated acute myeloid leukemia. Drugs used in chemotherapy, such as cytarabine, daunorubicin hydrochloride, idarubicin, and vorinostat, work in different ways to stop the growth of cancer cells, either by killing the cells, stopping them from dividing, or by stopping from spreading. Giving more than one drug (combination chemotherapy) and giving the drugs in different doses and in different combinations may kill more cancer cells. It is not yet known which combination chemotherapy is more effective in treating acute myeloid leukemia.

Acute Myeloid LeukemiaUntreated Adult Acute Myeloid Leukemia

National Cancer Institute (NCI)754 participantsStarted Feb 2013

Birmingham, Alabama, United States • Anchorage, Alaska, United States • Anchorage, Alaska, United States +444 more locations

Akt Inhibitor MK2206 in Treating Patients With Advanced Breast Cancer

Cytarabine and Daunorubicin Hydrochloride or Idarubicin and Cytarabine With or Without Vorinostat in Treating Younger Patients With Previously Untreated Acute Myeloid Leukemia

Find Trials by Condition in Boston

Myocardial Stress Perfusion Imaging With Dual Source CT

Safety and Efficacy Study of a Protease Activated Receptor-4 Antagonist Being Tested to Reduce the Chances of Having Additional Strokes or "Mini Strokes"

A Study to Determine the Efficacy and Safety of Lenalidomide in Patients With Mantle Cell NHL Who Have Relapsed or Progressed After Treatment With Bortezomib or Are Refractory to Bortezomib. The "EMERGE" Trial

Collateral Ligation in Failing Fistulas

Safety and Efficacy of CC-486 in Previously Treated Patients With Locally Advanced or Metastatic Nasopharyngeal Carcinoma

Vadastuximab Talirine (SGN-CD33A; 33A) Combined With Azacitidine or Decitabine in Older Patients With Newly Diagnosed Acute Myeloid Leukemia

Idiopathic Intracranial Hypertension Treatment Trial

Harnessing the Effect of an Open-Label Placebo on Fatigue in Cancer Survivors

Cixutumumab and Temsirolimus in Treating Younger Patients With Recurrent or Refractory Sarcoma

Use of the Leva Incontinence System in Treating Bladder Incontinence.

MySafeRx & MedicaSafe Open-Label Buprenorphine Induction and Lapse Evaluation (MyMOBILE)

A Long-Term Safety Study of ALKS 5461

A 24-week Open-Label, Phase 3b Trial With a 28-week Extension to Evaluate the Efficacy and Safety of Saxagliptin Co-administered With Dapagliflozin Compared to Insulin Glargine in Subjects withType 2 Diabetes Who Have Glycemic Control on Metformin

The Health Check-Up for Expectant Moms

Masitinib in Combination With Gemcitabine for Treatment of Patients With Advanced/Metastatic Pancreatic Cancer

Study Evaluating CMC-544 In B-Cell Non-Hodgkin's Lymphoma

A Study of Prexasertib (LY2606368) in Combination With Ralimetinib in Participants With Advanced or Metastatic Cancer

Retrospective Observational Study Investigating Fluciclovine (18F) (FACBC)