Clinical Trials in Boston

Showing 10161-10180 of 15,299 trials

Effect of D-cycloserine Plus Cognitive Behavioral Therapy on People With Social Phobia

NCT00515879

This study will assess the effectiveness of D-cycloserine combined with cognitive-behavior therapy in treating people with social anxiety disorder.

Social Anxiety Disorder

Boston University Charles River Campus169 participantsStarted Dec 2007

Boston, Massachusetts, United States

COMPLETEDPhase 3< 1 mile

Clinical Study of Macitentan in Patients With Pulmonary Arterial Hypertension to Psychometrically Validate the PAH-SYMPACT Instrument

NCT01841762

SYMPHONY is prospective, multi-center, open-label, single-arm, Phase 3b psychometric validation study of the PAH-SYMPACT, a new quality of life questionnaire for patients with pulmonary arterial hypertension. Patients will be in the study for 5 1/2 months, 4 months of which they will receive macitentan, 10 mg, once daily. The primary objectives are to demonstrate the final content validity of the PAH SYMPACT instrument, to demonstrate the psychometric characteristics of reliability and construct validity of the PAH-SYMPACT instrument, and to demonstrate the ability of the PAH SYMPACT instrument to detect change. The secondary objective is to assess the safety of macitentan in patients with pulmonary arterial hypertension. The exploratory objective is to explore the effects of macitentan on PAH symptoms and their impact (as measured by the PAH-SYMPACT) in patients with pulmonary arterial hypertension.

Pulmonary Arterial Hypertension

Actelion284 participantsStarted Apr 2013

Birmingham, Alabama, United States • Birmingham, Alabama, United States • Phoenix, Arizona, United States +78 more locations

Effect of D-cycloserine Plus Cognitive Behavioral Therapy on People With Social Phobia

Clinical Study of Macitentan in Patients With Pulmonary Arterial Hypertension to Psychometrically Validate the PAH-SYMPACT Instrument

Find Trials by Condition in Boston

Detect Fluid Early From Intra-thoracic Impedance Monitoring

Randomized Study Comparing Local Tumor Control After Post-Operative Single-Fraction or Hypofractionated Stereotactic Radiosurgery in the Treatment of Spinal Metastases

A Trial of SAMe for Treatment-Resistant Bipolar Depression

A Sustainable Approach to Increasing Cancer Screening

Machine Learning to Predict Clinical Response to TMS

Efficacy and Safety Evaluation of AN2690 Topical Solution to Treat Onychomycosis of the Toenail

Combined Antioxidant and Preeclampsia Prediction Studies (CAPPS)

Trial of Progesterone in Twins and Triplets to Prevent Preterm Birth (STTARS)

Thyroid Therapy for Mild Thyroid Deficiency in Pregnancy

Study to Assess the Efficacy and Safety of PT003, PT005, and PT001 in Subjects With Moderate to Very Severe COPD

Evaluate Risk/Benefit of Nab Paclitaxel in Combination With Gemcitabine and Carboplatin Compared to Gemcitabine and Carboplatin in Triple Negative Metastatic Breast Cancer (or Metastatic Triple Negative Breast Cancer)

Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Septic Shock

A Study to Assess the Safety of a Potential New Drug in Comparison to the Standard Practice of Dosing With Warfarin for Non-valvular Atrial Fibrillation

A Phase I, Open-Label, 2 Part Multicentre Study to Assess the Safety and Efficacy of Olaparib in Combination With Carboplatin in Patients With Advanced HER-2 Negative Breast Cancer

A Phase II Study to Evaluate Safety and Efficacy of ALX-0061 in Subjects With Systemic Lupus Erythematosus

GLobal Assessment of Plaque reGression With a PCSK9 antibOdy as Measured by intraVascular Ultrasound

Irrigated Ablation System Evaluation for Atrial Fibrillation (AF)

Heart Outcomes Prevention and Evaluation 4