Clinical Trials in Boston

Showing 841-860 of 8,503 trials

Well-being in IBS: Strengths and Happiness (WISH) 2.0

NCT06866106

The purpose of this study is to examine the feasibility, acceptability, preliminary effects, and candidate gut-brain mechanisms of an optimized positive psychology (PP) intervention for patients with irritable bowel syndrome (IBS), entitled "WISH," compared to an educational control intervention.

Irritable Bowel Syndrome

Massachusetts General Hospital50 participantsStarted Oct 2025

Boston, Massachusetts, United States

ACTIVE_NOT_RECRUITINGPHASE1< 1 mile

NeoVax Plus Ipilimumab in Renal Cell Carcinoma

NCT02950766

This research study is evaluating a new type of Kidney Cancer vaccine called "Personalized NeoAntigen Cancer Vaccine"as a possible treatment for Kidney Cancer. The following intervention will be involved in this study: * Personalized Neoantigen Vaccine * Poly-ICLC (Hiltonol) * Ipilimumab

Kidney Cancer

Patrick Ott, MD, PhD19 participantsStarted Mar 2019

Boston, Massachusetts, United States

RECRUITINGPHASE1< 1 mile

A Phase 1/1b Study of IAM1363 in HER2 Cancers

NCT06253871

This is a Phase 1/1b open-label, multi-center dose escalation and dose optimization study designed to evaluate the safety and preliminary efficacy of IAM1363 in participants with advanced cancers that harbor HER2 alterations.

HER2 Mutation-Related TumorsHER2HER2-positive Breast Cancer+10 more

Iambic Therapeutics, Inc243 participantsStarted Mar 2024

La Jolla, California, United States • Los Angeles, California, United States • Aurora, Colorado, United States +42 more locations

Well-being in IBS: Strengths and Happiness (WISH) 2.0

NeoVax Plus Ipilimumab in Renal Cell Carcinoma

A Phase 1/1b Study of IAM1363 in HER2 Cancers

Find Trials by Condition in Boston

A Phase 2b Study of Zagociguat in Patients With MELAS

Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Severe β-Hemoglobinopathies

Global Open-Label Extension Study of Del-desiran for the Treatment of DM1

A Study of Novel Anti-cancer Agents in Patients With Metastatic Triple Negative Breast Cancer

Montalcino Aortic Consortium: Precision Medicine for Heritable Thoracic Aortic Disease

Gaining Optimism After Weight Loss Surgery (GOALS) I

A Study of AAV2-hAQP1 Gene Therapy in Participants With Radiation-Induced Late Xerostomia

Phase 3 Study on the Efficacy and Safety of Human Plasma Derived Antithrombin (Atenativ) in Heparin-Resistant Patients Scheduled to Undergo Cardiac Surgery Necessitating Cardiopulmonary Bypass

Task-Shifting for Youth Suicide Prevention

Team Science (The Liver Health Study)

A Study to Evaluate Efficacy and Safety of Povorcitinib in Participants With Nonsegmental Vitiligo (STOP-V2)

A Study to Find a Suitable Dose of BI 765883 and to Test Whether it Helps People With Advanced Pancreatic Cancer When Taken Alone or Together With Chemotherapy

A Study About How TAK-881 is Processed by the Body and Side Effects in People With Primary Immunodeficiency Diseases

A Study of BMS-986482 Alone or as Combination Therapy in Participants With Advanced Solid Tumors

Roll-over Study to Allow Access to Certinib (LDK378) for Patients Who Are on Ceritinib Treatment in a Novartis-sponsored Study

A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK), and Preliminary Anticancer Activity of GSK4524101 Alone or With Niraparib in Participants With Solid Tumors

A Study to Assess Bioequivalence of Two Subcutaneous (SC) Formulations of Ocrelizumab in Participants With Multiple Sclerosis (MS)