Clinical Trials in Boston

Showing 741-760 of 17,836 trials

INHALE-1st: Afrezza® For Youth With Newly-Diagnosed Type 1 Diabetes

NCT07224321

INHALE-1st is a Phase 2, single-arm, multi-center, clinical study evaluating the safety and efficacy of Afrezza in combination with subcutaneously-injected basal insulin (BI) for youth 10 to \<18 years old with newly diagnosed stage 3 type 1 diabetes (T1D). The study will also evaluate the effect of an Afrezza plus BI reigmen on participant and parent/legally authorized representative satisfaction. Participants will be followed for 13 weeks during the main phase followed by an optional Extension Phase for participants continuing to use Afrezza in combination with BI for up to 26 weeks.

Type 1 Diabetes Mellitus

Mannkind Corporation100 participantsStarted Feb 2026

Los Angeles, California, United States • San Francisco, California, United States • Aurora, Colorado, United States +7 more locations

RECRUITINGPhase 1< 1 mile

TLN-372 in Advanced KRAS Mutant Solid Tumors

NCT07204340

The primary purpose of this study is to evaluate the safety, pharmacokinetics, and anti-tumor activity of TLN-372 as a single agent and in combination with other anti-tumor agents, in patients with advanced KRAS mutant solid tumors

KRAS Mutant Solid Tumors

Treeline Biosciences, Inc.240 participantsStarted Sep 2025

Birmingham, Alabama, United States • Boston, Massachusetts, United States • Grand Rapids, Michigan, United States +8 more locations

INHALE-1st: Afrezza® For Youth With Newly-Diagnosed Type 1 Diabetes

TLN-372 in Advanced KRAS Mutant Solid Tumors

Find Trials by Condition in Boston

IVIG for Infection Prevention After CAR-T-Cell Therapy

Efficacy and Tolerability of Rimegepant for the Acute Treatment of Migraine in Adults Unsuitable for Triptan Use

A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)

A Study to Evaluate the Effectiveness of Long-acting (LA) Cabotegravir (CAB) + Rilpivirine (RPV) LA When Given to Participants With Detectable HIV-1

A Randomized Controlled Trial of a Smartphone Delivered Treatment for Suicidal Thoughts and Behavior

A Study to Assess the Effectiveness and Safety of Irinotecan Liposome Injection, 5-fluorouracil/Leucovorin Plus Oxaliplatin in Patients Not Previously Treated for Metastatic Pancreatic Cancer, Compared to Nab-paclitaxel+Gemcitabine Treatment

Collagen-targeted PET Imaging for Early Interstitial Lung Disease

Surgery in Treating Patients With Early Stage Anal Canal or Perianal Cancer and HIV Infection

A Study to Evaluate the Efficacy and Safety of DNTH103 in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CAPTIVATE)

First-in-Human Study of DS-3939a in Participants With Advanced Solid Tumors

Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype

Study of Oral TLR8 Agonist Selgantolimod on HBsAg in Participants With Both Chronic Hepatitis B and HIV

A Study to Learn About the Study Medicine PF-08052667 in People With Bladder Cancer

Efficacy and Safety of MET097 Once-Weekly in People With Overweight or Obesity

A Clinical Study of Tulisokibart (MK-7240) to Treat Radiographic Axial Spondyloarthritis (MK-7240-013)

Pooled Analysis of Single-arm Studies of Budesonide/Glycopyrronium/Formoterol (BGF) in Routine Care Setting

Non-inferiority Study of Frexalimab Subcutaneous Administration Compared to Intravenous Administration in Adult Participants With Multiple Sclerosis

A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)