Clinical Trials in Boston

Showing 7081-7100 of 17,836 trials

Phase I AZD2281/Cisplatin in Advanced Solid Tumour Patients

NCT00782574

A Phase I study to assess the safety and tolerability of AZD2281 in combination with Cisplatin in patients with advanced Solid Tumours. This is an open label-dose finding; to establish the maximum tolerated dose of AZD2281 combined with Cisplatin in patients with advanced solid tumours. Approximately 50 (max 60) patients from 2 countries will be enrolled

Advanced Solid Tumors

AstraZeneca57 participantsStarted Nov 2008

Boston, Massachusetts, United States • Boston, Massachusetts, United States • Barcelona, Spain

COMPLETEDPhase 3< 1 mile

Filgotinib in the Induction and Maintenance of Remission in Adults With Moderately to Severely Active Crohn's Disease

NCT02914561

The primary objectives of this study are to evaluate the safety and efficacy of filgotinib during induction and maintenance treatment of moderately to severely active Crohn's disease (CD) in participants who are biologic-naive and biologic-experienced. Participants who complete the study, or do not meet protocol response or remission criteria at Week 10 will have the option to enter a separate long-term extension (LTE) study (Study GS-US-419-3896).

Crohn's Disease

Lakefront Biotherapeutics NV1,372 participantsStarted Oct 2016

Dothan, Alabama, United States • Sun City, Arizona, United States • Coronado, California, United States +510 more locations

Phase I AZD2281/Cisplatin in Advanced Solid Tumour Patients

Filgotinib in the Induction and Maintenance of Remission in Adults With Moderately to Severely Active Crohn's Disease

Find Trials by Condition in Boston

Characterizing the Electroencephalogram Signature of Fentanyl During Induction of General Anesthesia

A Study of OCE-205 in Participants With Cirrhosis With Ascites Who Developed Hepatorenal Syndrome-Acute Kidney Injury

A Clinical Trial to Confirm Safety & Effectiveness of the SYNERGY 4.50 mm and 5.00 mm Stent for Treatment of Atherosclerotic Lesion(s)

Robot for Alleviating Loneliness and Engaging Nursing Home Residents

Sorafenib Tosylate Following a Liver Transplant in Treating Patients With Liver Cancer

Extracellular RNAs in Relation to Cardiometabolic Risk

Shockwave Medical Peripheral Lithoplasty System Study for PAD (Disrupt PAD III)

A Study to Evaluate SAGE-217 in Participants With Severe Postpartum Depression

A Study to Assess the Safety, Efficacy and Tolerability of AZD8233 Treatment in Participants With Hyperlipidaemia

Study to Test the Efficacy and Safety of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adults With Drug-resistant Epilepsy

AkLief Evaluation in Acne-induced Post-Inflammatory Hyperpigmentation

A Study of [225Ac]-FPI-1966 in Participants With Advanced Solid Tumours

Derazantinib in Subjects With FGFR2 Gene Fusion-, Mutation- or Amplification- Positive Inoperable or Advanced Intrahepatic Cholangiocarcinoma

Intranasal Oxytocin for Frontotemporal Dementia

Maximal Usage Pharmacokinetics and Safety of ARQ-151 in Children With Plaque Psoriasis (ARQ-151-215)

A Clinical Study Evaluating Nivolumab-containing Treatments in Patients With Advanced Non-small Cell Lung Cancer After Failing Previous PD-1/(L)1 Therapy and Chemotherapy

A Study to Determine the Efficacy and Safety of Luspatercept in Adults With Non Transfusion Dependent Beta (β)-Thalassemia

Survival Prolongation by Rationale Innovative Genomics