Clinical Trials in Boston

Showing 6901-6920 of 13,548 trials

Preserved Umbilical Vein Use as Autologous Shunt Conduits in Neonatal Cardiac Surgery

NCT02766998

This is a prospective, single center, safety and feasibility trial to evaluate the use of autologous umbilical vein as shunts or conduits in neonatal cardiac surgery. Subjects will be identified here at the Advanced Fetal Care Center (AFCC) following diagnosis of congenital heart disease (CHD) with single ventricle physiology of the fetus via fetal echocardiogram. At time of cesarean section or vaginal delivery, umbilical cord will be harvested in a sterile fashion and the umbilical vein will be dissected free and preserved until first clinically indicated Stage I palliative procedure between day 3 and 7 of life. Subjects will be followed until their Stage II palliative procedure.

Congenital Heart Defects

Boston Children's Hospital2 participantsStarted May 2016

Boston, Massachusetts, United States

COMPLETEDPhase 2< 1 mile

CISPLATIN + AZD-1775 In Breast Cancer

NCT03012477

This research study is studying a combination of drugs as a possible treatment for triple-negative breast cancer that has spread to other areas of the body. The names of the study interventions involved in this study are: * Cisplatin * AZD1775

Triple-negative Metastatic Breast Cancer

Dana-Farber Cancer Institute34 participantsStarted Jan 2017

Boston, Massachusetts, United States

COMPLETEDPhase 2< 1 mile

Safety and Efficacy of AVP-923 in the Treatment of Central Neuropathic Pain in Multiple Sclerosis

NCT01324232

The objectives of the study are to evaluate the safety, tolerability, and efficacy of 3 doses of AVP-923 capsules in the treatment of central neuropathic pain in participants with multiple sclerosis.

Central Neuropathic PainMultiple Sclerosis

Avanir Pharmaceuticals209 participantsStarted Sep 2011

Cullman, Alabama, United States • Phoenix, Arizona, United States • Berkeley, California, United States +69 more locations

Preserved Umbilical Vein Use as Autologous Shunt Conduits in Neonatal Cardiac Surgery

CISPLATIN + AZD-1775 In Breast Cancer

Safety and Efficacy of AVP-923 in the Treatment of Central Neuropathic Pain in Multiple Sclerosis

Find Trials by Condition in Boston

A Depot Formulation of Sunitinib Malate (GB-102) in Subjects With Diabetic Macular Edema and Retinal Vein Occlusion

Care Transition Intervention for Patients With Cancer

Risk Stratification of Rapid Disease Progression in Children With Crohn's Disease

Optimizing Smoke-free Residential Housing Policies

Homoharringtonine (Omacetaxine Mepesuccinate) in Treating Patients With Chronic Myeloid Leukemia (CML) With the T315I BCR-ABL Gene Mutation

Comparative Effectiveness and Safety of Tiotropium and Olodaterol in Comparison to LABA/ICS

Fabry Outcome Survey (FOS)

Medroxyprogesterone Acetate With or Without Entinostat Before Surgery in Treating Patients With Endometrioid Endometrial Cancer

Improving the Experience of Exercise Among Individuals With Internalized Weight Bias Using Acceptance-based Strategies

Evaluation of Two Doses of QVAR by Breath Operated and Metered Dose Inhalers in Asthmatic Children

Rituximab and Combination Chemotherapy in Treating Patients With Diffuse Large B-Cell Non-Hodgkin's Lymphoma

STEP 1: Research Study Investigating How Well Semaglutide Works in People Suffering From Overweight or Obesity

Pacritinib Versus Best Available Therapy to Treat Patients With Myelofibrosis and Thrombocytopenia

InterStim Basic Evaluation Lead Post-Market Clinical Follow-up Study

Trial of a Gastrin Receptor Antagonist in Barrett's Esophagus

Study of MK-7162 in Combination With Pembrolizumab (MK-3475) in Adult Participants With Advanced Solid Tumors (MK-7162-002)

Benefit of Dual-chamber Pacing With Closed Loop Stimulation (CLS) in Tilt-induced Cardioinhibitory Reflex Syncope