Clinical Trials in Boston

Showing 6341-6360 of 13,548 trials

Pharmacological Activation of HMN for OSA Aim 2

NCT03858751

Obstructive sleep apnea (OSA) is common and has major health implications but treatment options are limited. OSA patients show a marked reduction in upper airway (UA) dilator muscle activity at sleep onset and this phenomenon leads to increased collapsibility of UA compared to normal subjects. In this protocol the investigators will test the effect of LTM1201AZ, LTM1201AT, LTM1201AD, LTM1201AG administered before sleep on OSA phenotype traits and OSA severity during sleep.

Obstructive Sleep Apnea

Brigham and Women's Hospital16 participantsStarted Mar 2019

Boston, Massachusetts, United States

WITHDRAWNPhase 2/3< 1 mile

Nitrous Oxide for Pain Management During IUD Insertion in Nulliparous Adolescent Women

NCT04089852

This pilot study aims to assess the feasibility, acceptability, and effectiveness of using nitrous oxide (N2O) sedation for intrauterine device (IUD) insertions for nulliparous adolescent and young adult women in a primary care clinic setting.

Contraceptive DevicesLong-Acting Reversible ContraceptionAnalgesia+2 more

Boston Children's HospitalStarted Jun 2021

Boston, Massachusetts, United States

Pharmacological Activation of HMN for OSA Aim 2

Nitrous Oxide for Pain Management During IUD Insertion in Nulliparous Adolescent Women

Find Trials by Condition in Boston

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of ACH-0137171 in Participants With Chronic Hepatitis C Infection

Mental Training for Adults With Mild Cognitive Impairment

Optimization and Multi-Site Feasibility of Yoga for Chronic Pain in People in YOGAMAT-II - Phase I

A Study Of PF-05212384 In Combination With Other Anti-Tumor Agents and in Combination With Cisplatin in Patients With Triple Negative Breast Cancer in an Expansion Arm (TNBC)

A Study of Experimental Medication BMS-986036 in Adults With Nonalcoholic Steatohepatitis (NASH) and Stage 3 Liver Fibrosis

Neural Correlates of Successful Cognitive Aging

LIFT Home Study of Non-Invasive ARC Therapy for Spinal Cord Injury

Developing a Positive Psychology Intervention to Promote Health Behaviors in Metabolic Syndrome: RCT

Corticosteroid Lumbar Epidural Analgesia for Radiculopathy

Stereotactic Radiation Therapy With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases

A Phase 2 Study Evaluating the Safety and Efficacy of Netarsudil Ophthalmic Solution in Patients With Corneal Edema Due to Fuchs Corneal Dystrophy

A Comparison Study of LY2140023 and Aripiprazole in Schizophrenia Patients

Safety, Tolerability, and Efficacy of AXA1125 in NASH With Fibrosis

A Study of LY2140023 in Schizophrenia Patients With Prominent Negative Symptoms

A Double-blind Study of Paclitaxel in Combination With Reparixin or Placebo for Metastatic Triple-Negative Breast Cancer

Adapalene 0.3% - Benzoyl Peroxide 2.5% Gel and Risk of Formation of Atrophic Acne Scars

Study to Assess if ABP798 is Safe & Effective in Treating Non Hodgkin Lymphoma Compared to Rituximab

Phase 1 Study to Assess the Safety, PK and PD of INBRX-101 in Adults With Alpha-1 Antitrypsin Deficiency