Clinical Trials in Boston

Showing 541-560 of 8,503 trials

GCC19CART for Patients With Metastatic Colorectal Cancer

NCT05319314

Study ICT-GCC19CART-US-001 (CARAPIA-1) is a Phase 1 study evaluating the safety, tolerability, clinical activity, pharmacokinetics and pharmacodynamics of GCC19CART in subjects with relapsed or refractory metastatic colorectal cancer.

Colorectal Cancer

Lyell Immunopharma, Inc.30 participantsStarted Aug 2022

Duarte, California, United States • San Francisco, California, United States • Aurora, Colorado, United States +1 more locations

RECRUITINGPHASE2< 1 mile

Ribociclib And Endocrine Treatment of Physician's Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer

NCT05467891

This is an open label, multicenter, single arm phase II study to evaluate the efficacy and safety of ribociclib and ET in patients with locoregional recurrence of HR-positive, HER2-negative breast cancer.

Locoregional RecurrenceHormone Receptor-positive Breast CancerHER2-negative Breast Cancer

Oana Danciu200 participantsStarted Sep 2022

Birmingham, Alabama, United States • Phoenix, Arizona, United States • Orlando, Florida, United States +17 more locations

GCC19CART for Patients With Metastatic Colorectal Cancer

Ribociclib And Endocrine Treatment of Physician's Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer

Find Trials by Condition in Boston

Oral N-acetylcysteine for Retinitis Pigmentosa

A 52-Week Study of Ritlecitinib Oral Capsules in Adults and Adolescents With Nonsegmental Vitiligo (Active and Stable) Tranquillo

A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)

A Clinical Trial to Assess COM503 in Participants With Advanced Solid Malignancies

Preliminary Efficacy Trial of a Digital Intervention for Depression and Cannabis Use

A Clinical Trial to Evaluate the Safety and Efficacy of COM701 in Relapsed Platinum Sensitive Ovarian Cancer

Behavioral Activation for Independence in Older Veterans

A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)

A Study to Assess the Efficacy and Safety of Satralizumab in Duchenne Muscular Dystrophy (DMD)

Study Evaluating Tarlatamab After Chemoradiotherapy in Limited-Stage Small-Cell Lung Cancer (LS-SCLC)

A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria

A Study to Evaluate the Safety and Effectiveness of ALKS 2680 in Subjects With Narcolepsy Type 2

Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers

A Phase Ⅲ Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer

Debio 0123 in Combination With Carboplatin and Etoposide in Adult Participants With Small Cell Lung Cancer That Recurred or Progressed After Previous Standard Platinum-Based Therapy

SMP-3124LP in Adults With Advanced Solid Tumors

A Study to Evaluate Subcutaneous Zilucoplan in Pediatric Participants With Generalized Myasthenia Gravis

A Study of Rozanolixizumab in Pediatric Study Participants With Moderate to Severe Generalized Myasthenia Gravis