Clinical Trials in Boston

Showing 5441-5460 of 17,836 trials

"Prapela® SVS Incubator Pad for Apnea of Prematurity

NCT06374147

The study proposes to complete the development of and then establish the safety, efficacy, and clinical risk/benefit of a novel hospital incubator pad with stochastic vibrotactile stimulation (SVS) that will provide a complementary treatment and the first improvement in the clinical management of apnea of prematurity (AOP) in over 20 years. Currently, the only approved therapy for AOP is Caffeine Citrate. The SVS mattress pad can prove to be an effective, non-invasive adjunct to Caffeine Citrate for preterm infants with potential to shorten the need for respiratory support as well as overall shortened length of stay.

Apnea of Prematurity

Tufts Medical Center140 participantsStarted Feb 2025

Birmingham, Alabama, United States • Boston, Massachusetts, United States

COMPLETEDPhase 3< 1 mile

Comparison of Two Medications Aimed at Slowing Aortic Root Enlargement in Individuals With Marfan Syndrome

NCT00429364

Marfan syndrome is a hereditary connective tissue disorder. Many individuals with this condition die because of the associated heart and blood vessel abnormalities. This study will compare the effectiveness of two medications, losartan and atenolol, at slowing aortic root enlargement in individuals with Marfan syndrome.

Marfan Syndrome

Carelon Research608 participantsStarted Jan 2007

Los Angeles, California, United States • Palo Alto, California, United States • San Diego, California, United States +23 more locations

"Prapela® SVS Incubator Pad for Apnea of Prematurity

Comparison of Two Medications Aimed at Slowing Aortic Root Enlargement in Individuals With Marfan Syndrome

Find Trials by Condition in Boston

Study to Assess the Safety and Biological Activity of AMX0035 for the Treatment of Alzheimer's Disease

Study of Efficacy and Safety of LEE011 in Postmenopausal Women With Advanced Breast Cancer

MGD019 DART® Protein in Unresectable/Metastatic Cancer

Changes in NT-proBNP, Safety, and Tolerability in HFpEF Patients With a WHF Event (HFpEF Decompensation) Who Have Been Stabilized and Initiated at the Time of or Within 30 Days Post-decompensation (PARAGLIDE-HF)

Study of Lanreotide Autogel in Non-functioning Entero-pancreatic Endocrine Tumours

T-DM1+Pertuzumab in Pre-OP Early-Stage HER2+ BRCA

AZithromycin Therapy in Preschoolers With a Severe Wheezing Episode Diagnosed at the Emergency Department

The MIRIA Acne Scar Study

IMPRINT VR Trainer Evaluation

A Study to Test the Effect of Different Doses of BI 1358894 and Quetiapine in People With Depression

Innoventric Trillium™ Stent Graft Early Feasibility Study (EFS)

Observational Study of Persistence on Bafiertam Treatment in Routine Clinical Practice

A Study of Increasing Strengths, Safety and Efficacy of Two Formulas of LEO 43204 on the Face or the Chest in Patients With Actinic Keratosis

Effect of Calcipotriol Plus Hydrocortisone Ointment on the Adrenal Hormone Balance and Calcium Metabolism in Patients With Psoriasis Vulgaris on the Face and Skin Folds

A Study Evaluating ANV600 Single Agent or in Combination with Pembrolizumab in Participants with Advanced Solid Tumors (EXPAND-1)

CorPath® GRX Neuro Study

A Study to Compare the Safety and Efficacy of an Aromatase Inhibitor in Combination With Lapatinib, Trastuzumab or Both for the Treatment of Hormone Receptor Positive, HER2+ Metastatic Breast Cancer

Rapid On Site Evaluation of Pleural Touch Preparations in Diagnosing Malignant Pleural Effusion in Patients Undergoing Pleuroscopy