Clinical Trials in Boston

Showing 5261-5280 of 13,548 trials

A Study to Evaluate Rucaparib in Combination With Other Anticancer Agents in Participants With a Solid Tumor (SEASTAR)

NCT03992131

This is an open label, Phase 1b/2 study with multiple treatment arms evaluating the safety, tolerability, pharmacokinetics (PK), and preliminary efficacy of rucaparib in combination with a second anticancer therapy in participants with an advanced/metastatic solid malignancy (Phase 1b), followed by evaluation of the combination in one or more specific participant populations in an expansion phase (Phase 2 cohorts).

Ovarian CancerTriple-negative Breast CancerUrothelial Carcinoma+1 more

pharmaand GmbH25 participantsStarted Jun 2019

Boston, Massachusetts, United States • Nashville, Tennessee, United States • Houston, Texas, United States

UNKNOWN< 1 mile

Diagnostic Performance of Small RNA Blood Test in Patients Undergoing Follow-up Imaging After Positive Low Dose CT Screening for Cancer of the Lung

NCT05987189

2,000 individuals, aged 50-80 who have received a lung-RADS category 3 or 4 result on a LDCT screening study and who are scheduled for follow-up diagnostic imaging study, biopsy, clinical consultation or surgical appointment at one of the participating hospitals.

Lung Cancer

Hummingbird Diagnostics2,000 participantsStarted Oct 2023

Atlanta, Georgia, United States • Boston, Massachusetts, United States • Detroit, Michigan, United States +5 more locations

A Study to Evaluate Rucaparib in Combination With Other Anticancer Agents in Participants With a Solid Tumor (SEASTAR)

Diagnostic Performance of Small RNA Blood Test in Patients Undergoing Follow-up Imaging After Positive Low Dose CT Screening for Cancer of the Lung

Find Trials by Condition in Boston

The Acute Impact of Yoga-based Stretching on Inflammation and Its Resolution

Study of CB-103 in Adult Patients With Advanced or Metastatic Solid Tumours and Haematological Malignancies

Losartan in Prevention of Radiation-Induced Heart Failure

A Phase I/II Study of MLN0128 in Metastatic Anaplastic Thyroid Cancer and Incurably Poorly Differentiated or Radioidodine Refractory Differentiated Thyroid Cancer

Trial To Test Safety And Efficacy Of Vaccination For Incurable HPV 16-Related Oropharyngeal, Cervical And Anal Cancer

Congenital Heart Disease: Impact on Learning and Development in Down Syndrome (CHILD-DS)

Clinical Research Study With Clazosentan to Evaluate Its Effects on Preventing Complications Due to the Narrowing of the Blood Vessels (Vasospasm) in the Brain, Caused by Bleeding Onto the Surface of the Brain

A Study of PTC923 in Participants With Phenylketonuria

Using Microbial Genomics to Elucidate the Source of Central-line Associated Bloodstream Infections

A Study of OV101 in Individuals With Angelman Syndrome (AS)

Observational Peripheral IV Insertion Study

A Study of Ocrelizumab in Participants With Primary Progressive Multiple Sclerosis

B0151005 Open-Label Extension Study

The Effect of In-utero Exposure to Metformin in 5-11 Year Old Offspring of Mothers in the MiTy Trial

Study Evaluating Betrixaban in Pediatric Participants

Bomedemstat (IMG-7289/MK-3543) in Participants With Myelofibrosis (IMG-7289-CTP-102/MK-3543-002)

Non-Myeloablative Conditioning and Bone Marrow Transplantation

International Chronic Myeloid Leukemia Pediatric Study