Clinical Trials in Boston

Showing 5041-5060 of 17,836 trials

Project 4: Ambulatory Biofeedback and Voice Therapy for Patients With Vocal Hyperfunction

NCT05970562

Vocal hyperfunction (VH) is the most commonly treated class of voice disorders by speech-language pathologists and voice therapy is the primary curative treatment. Patients and clinicians report that generalizing improved voicing into daily life is the most significant barrier to successful therapy. We will test if extending biofeedback into the patient's daily life using ambulatory voice monitoring will significantly improve generalization during therapy and if individual patient factors, like how easily they can modify their voice and engagement during therapy, moderate the effects of the biofeedback.

Voice DisordersVocal Fold PolypVocal Nodules in Adults+1 more

Massachusetts General Hospital100 participantsStarted Mar 2024

Boston, Massachusetts, United States • Boston, Massachusetts, United States

COMPLETEDNA< 1 mile

Trauma Informed Guilt Reduction Therapy

NCT02512445

The goal of this project is to determine if a 6-session psychotherapy intervention will help Veterans feel less deployment-related guilt and less distress related to their guilt. Half of the participants will receive the guilt focused intervention and half will receive a supportive intervention. A supplemental pilot study added in FY2021 will examine the intervention for pandemic-related guilt events.

GuiltShamePost-traumatic Stress Disorders

Veterans Medical Research Foundation145 participantsStarted Oct 2015

San Diego, California, United States • Boston, Massachusetts, United States • Providence, Rhode Island, United States

Project 4: Ambulatory Biofeedback and Voice Therapy for Patients With Vocal Hyperfunction

Trauma Informed Guilt Reduction Therapy

Find Trials by Condition in Boston

Study of TVB-2640 in Subjects With Nonalcoholic Steatohepatitis (NASH)

Effect of a Probiotic Mixture on the Gut Microbiome and Fatigue in Patients With Quiescent Inflammatory Bowel Disease

Safety, Feasibility, and Efficacy of Non-invasive Vagus Nerve Stimulation (nVNS) in the Treatment of Aneurysmal Subarachnoid Hemorrhage

Savolitinib Plus Durvalumab Versus Sunitinib and Durvalumab Monotherapy in MET-Driven, Unresectable and Locally Advanced or Metastatic PRCC

The Impact of Overnight Nutrition Support on Sleep and Circadian Rhythm Disruption in the ICU

Optimizing Feedback-based Learning in Children With Developmental Language Disorder

COffee and Metabolites Modulating the Gut MicrobiomE in Colorectal caNCER

Interpretation Bias as a Mechanism of Treatment Response in OCD

A Multiple Health Behavior Change Intervention for Overweight and Obese Smokers

Enhancing the Effects of Adolescent Alcohol Treatment With Atomoxetine

A Research Study To See How Well an Eye Drop, SURF-100 (A Mycophenolic Acid/Betamethasone Sodium Phosphate Combination), Works and What Side Effects There Are in Subjects With Dry Eye Disease

A Study of Trastuzumab Deruxtecan (T-DXd) Versus Trastuzumab Emtansine (T-DM1) in High-risk HER2-positive Participants With Residual Invasive Breast Cancer Following Neoadjuvant Therapy (DESTINY-Breast05)

Study of Carfilzomib, Daratumumab and Dexamethasone for Patients With Relapsed and/or Refractory Multiple Myeloma.

Efficacy in iNPH Shunting (PENS) Trial

A 24 Week Trial to Compare the Efficacy and Safety of Delgocitinib Cream 20 mg/g Twice-daily With Alitretinoin Capsules Once-daily in Adult Participants With Severe Chronic Hand Eczema

Study of Adagloxad Simolenin (OBI-822)/OBI-821 in the Adjuvant Treatment of Patients With Globo H Positive TNBC

Adalimumab in JIA-associated Uveitis Stopping Trial

SIRT Followed by CIS-GEM Chemotherapy Versus CIS-GEM Chemotherapy Alone as 1st Line Treatment of Patients With Unresectable Intrahepatic Cholangiocarcinoma