Clinical Trials in Boston

Showing 4201-4220 of 13,548 trials

A Study of Ad26.COV2.S in Adults (COVID-19)

NCT04436276

The purpose of the study is to assess the safety, reactogenicity, and immunogenicity of Ad26.COV2.S at 2 dose levels, administered intramuscularly (IM) as a single-dose or 2-dose schedule, with a single booster vaccination administered in one cohort in healthy adults aged greater than or equal to (\>=) 18 to less than or equal to (\<=) 55 years and in adults aged \>= 65 years in good health with or without stable underlying conditions. The purpose of the study is also to assess the safety and reactogenicity of Ad26.COV2.S administered as ad hoc booster vaccination in healthy adults aged \>= 18 to \<= 55 years and in adults \>= 65 years in good health with or without stable underlying conditions.

Covid-19 Prevention

Janssen Vaccines & Prevention B.V.1,085 participantsStarted Jul 2020

San Diego, California, United States • Melbourne, Florida, United States • Peoria, Illinois, United States +9 more locations

COMPLETEDPhase 1< 1 mile

A Study of Guselkumab in Participants With Familial Adenomatous Polyposis

NCT03649971

The purpose of this study is to determine the effect of treatment with guselkumab in participants with familial adenomatous polyposis (FAP) on rectal/pouch polyp burden.

Adenomatous Polyposis Coli

Janssen Research & Development, LLC77 participantsStarted Nov 2018

Phoenix, Arizona, United States • Duarte, California, United States • New Haven, Connecticut, United States +29 more locations

A Study of Ad26.COV2.S in Adults (COVID-19)

A Study of Guselkumab in Participants With Familial Adenomatous Polyposis

Find Trials by Condition in Boston

Lifestyle, Exercise, and Nutrition Study Early After Diagnosis

Spinal Cord Stimulation vs. Medical Management for Low Back Pain (DISTINCT)

HERTHENA-Lung02: A Study of Patritumab Deruxtecan Versus Platinum-based Chemotherapy in Metastatic or Locally Advanced EGFRm NSCLC After Failure of EGFR TKI Therapy

Cabozantinib and Nivolumab for Carcinoid Tumors

Phase 2 Platform Study in Patients With Advanced Non-Small Lung Cancer Who Progressed on First-Line Osimertinib Therapy (ORCHARD)

Evaluation of Flash Continuous Glucose Monitoring to Reduce Hyperglycemia in People With T2 Diabetes

A Natural History Study of Biomarkers and Clinical Outcomes in Mucopolysaccharidosis Type IIIA (MPS IIIA; Sanfilippo Syndrome)

A Clinical Study to Evaluate the Efficacy of Activated Silk™ 27P-α in Subjects, Aged 35-65 Years of Age, to Improve the Signs of Aging, by Comparing to a Placebo

A Clinical Study to Evaluate the Efficacy of Activated Silk™ 27P-α in Subjects, Aged 35-65 Years of Age, to Improve the Signs of Aging

A Study of Loncastuximab Tesirine and Rituximab (Lonca-R) in Previously Untreated Unfit/Frail Participants With Diffuse Large B-cell Lymphoma (DLBCL)

Study of the Safety, Tolerability, Pharmacokinetics and Biomarker of DONQ52 in Celiac Disease Patients

A Study of Acute Respiratory Infections in Global Outpatient Setting

Avelumab in First-line NSCLC (JAVELIN Lung 100)

Tailored Axillary Surgery With or Without Axillary Lymph Node Dissection Followed by Radiotherapy in Patients With Clinically Node-positive Breast Cancer (TAXIS)

A Randomized Controlled Trial of TNK-tPA Versus Standard of Care for Minor Ischemic Stroke With Proven Occlusion

A Study on the Immune Response and Safety of an Adjuvanted Human Papillomavirus Vaccine When Given to Healthy Women 16 to 26 Years of Age

Efficacy and Safety of GWP42003-P Oral Solution in Children With Epilepsy With Myoclonic-atonic Seizures

A Study of Subcutaneously-administered Guselkumab Delivered by 3 Different Devices in Healthy Participants