Clinical Trials in Boston

Showing 3381-3400 of 17,836 trials

Oral Tafenoquine Plus Standard of Care Versus Placebo Plus Standard of Care for Babesiosis

NCT06207370

This study is a double-blind, randomized, multisite, placebo-controlled trial comparing the safety and efficacy of TQ versus placebo in patients hospitalized for babesiosis with low risk for relapsing disease who will also be administered a standard-of-care antimicrobial regimen (A/A) that is recommended in the 2020 IDSA guideline on the diagnosis and management of babesiosis.

Babesiosis

60 Degrees Pharmaceuticals LLC33 participantsStarted Jun 2024

Boston, Massachusetts, United States

Active Not RecruitingPhase 1< 1 mile

Ribociclib in Combination With Everolimus and Dexamethasone in Relapsed ALL

NCT03740334

This research study is evaluating a drug called ribociclib (LEE011) given in combination with everolimus and other standard of care chemotherapy drugs as a possible treatment for relapsed or refractory ALL. The names of the drugs involved in this study are: * ribociclib * everolimus * dexamethasone

Acute Lymphoblastic Leukemia ALL

Dana-Farber Cancer Institute45 participantsStarted Jan 2019

Aurora, Colorado, United States • Wilmington, Delaware, United States • Atlanta, Georgia, United States +9 more locations

Oral Tafenoquine Plus Standard of Care Versus Placebo Plus Standard of Care for Babesiosis

Ribociclib in Combination With Everolimus and Dexamethasone in Relapsed ALL

Find Trials by Condition in Boston

A Study of Repotrectinib Versus Crizotinib in Participants With Locally Advanced or Metastatic Tyrosine Kinase Inhibitor (TKI)-naïve ROS1-positive Non-Small Cell Lung Cancer (NSCLC) (TRIDENT-3)

Efficacy of Skin Cooling in Reducing Pain Associated With Non-invasive Treatments of Neurofibromatosis Type 1 Cutaneous Neurofibromas

A Study to Find Out How Safe REGN5668 is and How Well it Works In Adult Women When Given With Either Cemiplimab, or Cemiplimab + Fianlimab, or Ubamatamab

Chemotherapy Followed by Radiation Therapy in Treating Younger Patients With Newly Diagnosed Localized Central Nervous System Germ Cell Tumors

Post Approval Study (PAS) of the OPTIMIZER Smart and CCM Therapy

Adjunctive Motivational Alcohol Intervention to Prevent IPV

A Study to Evaluate Efficacy and Safety of GSK3858279 in Diabetic Peripheral Neuropathic Pain

Parallel-Arm Study to Compare AD109 to Placebo With Patients With OSA (SynAIRgy Study)

Flexible-Dose Trial in Early Parkinson's Disease (PD)

STENOVA - A Study to Evaluate Safety, Tolerability, PK and PD of AGMB-129 in Patients With Fibrostenotic Crohn's Disease

A Study of HyQvia in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) in Routine Clinical Care

LIONS (PLK4 Inhibitor in Advanced Solid Tumors)

A Study of Nivolumab in Participants With Hepatocellular Carcinoma Who Are at High Risk of Recurrence After Curative Hepatic Resection or Ablation

Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia

Trial of the F2 Filter and Delivery System for Embolic Protection During TAVR

A Study to Investigate Vamikibart in Participants With Uveitic Macular Edema

An Extension Study to Evaluate the Long-Term Safety and Efficacy of Votoplam in Participants With Huntington's Disease (HD)

A Study on the Safety of Ozanimod Exposure in Pregnant Women and Their Offspring