Clinical Trials in Boston

Showing 2521-2540 of 17,836 trials

Evaluation of Revumenib in Participants With Colorectal Cancer and Other Solid Tumors

NCT05731947

This study will evaluate the safety, tolerability, pharmacokinetics (PK), and anti-tumor activity of revumenib in participants with colorectal cancer (CRC) or other solid tumors who have failed at least 1 prior line of therapy.

Colorectal CancerSolid Tumors

Syndax Pharmaceuticals42 participantsStarted Apr 2023

Scottsdale, Arizona, United States • Boston, Massachusetts, United States • Manhattan, New York, United States +3 more locations

RECRUITINGPhase 2< 1 mile

BCL2i CLAG-M in R/R Acute Myeloid Leukemia

NCT06660368

This multicenter, open-label phase II study combines CLAG-based therapy with or without venetoclax in patients with relapsed or refractory (R/R) acute myeloid leukemia (AML) in order to improve measurable residual disease (MRD) clearance and event-free survival. Investigators hypothesize that the addition of venetoclax to CLAG-M in patients with relapsed or refractory AML is safe, and superior to CLAG-M alone in improving patient outcomes.

Relapsed or Refractory Acute Myeloid Leukemia (AML)

H. Lee Moffitt Cancer Center and Research Institute52 participantsStarted Nov 2024

Tampa, Florida, United States • Boston, Massachusetts, United States

Evaluation of Revumenib in Participants With Colorectal Cancer and Other Solid Tumors

BCL2i CLAG-M in R/R Acute Myeloid Leukemia

Find Trials by Condition in Boston

Home OCT-Guided Treatment Versus Treat and Extend for the Management of Neovascular AMD

Acalabrutinib + Liso-Cel In R/R Aggressive B-Cell Lymphomas

Feasibility Testing of a Tai Chi Program for Chemotherapy-Induced Peripheral Neuropathy Treatment (TCT)

A Study of PHN-010 in Patients With Advanced Solid Tumors

Infliximab for Treatment of Immune Checkpoint Inhibitor Colitis

EXHIT ENTRE Implementation Trial of High Intensity Versus Low Intensity Strategy

Evaluating BOSCC and ELSA as Outcome Measures in the Context of a JASPER Intervention Trial

A Study to Evaluate the Efficacy and Safety of Bimekizumab in the Treatment of Subjects With Active Psoriatic Arthritis

A Proof-of-concept Study to Examine QUC398 in Participants With Knee OA

Clinical Study of the Treovance Stent-Graft for Patients With Abdominal Aortic Aneurysms

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis

Study to Evaluate the Efficacy, Immunogenicity, and Safety of RSVpreF in Adults.

A Study of HMPL-306 in Advanced Hematological Malignancies With mIDH

Project CARE: An Integrated Treatment Adherence Program for Bipolar Disorder at the Time of Prison Release - Pilot RCT

A Study of a Novel Iron-based Phosphate Binder AP301 in Patients With Hyperphosphatemia in the U.S. and China

Primary Radiotherapy Versus Primary Surgery for HPV-Associated Oropharyngeal Cancer

Study to Compare Efficacy, Safety, and Immunogenicity of LUBT010 (Proposed Ranibizumab Biosimilar) and Lucentis® in Patients With Neovascular AMD

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Complement Inhibitors