Clinical Trials in Baltimore

Showing 8581-8600 of 17,842 trials

Biomarker-Driven Therapy With Nivolumab and Ipilimumab in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer Expressing AR-V7

NCT02601014

This phase II trial studies how well nivolumab and ipilimumab work in treating patients with hormone-resistant prostate cancer that has spread to other places in the body and express androgen receptor-variant-7 (AR-V7). Tumor cells expressing AR-V7 has been shown to be resistant to hormone therapy and some chemotherapy in patients with prostate cancer. Biomarker-driven therapy, such as nivolumab and ipilimumab, may work by blocking key biomarkers or proteins that help tumor cells to escape the immune system surveillance and this may help the immune system to kill tumor cells that express AR-V7.

Prostate CancerRecurrent Prostate CarcinomaStage IV Prostate Adenocarcinoma

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins32 participantsStarted Mar 2016

Baltimore, Maryland, United States

TERMINATEDPhase 2< 1 mile

Rollover Study of Cenicriviroc for the Treatment of Liver Fibrosis in Participants With Nonalcoholic Steatohepatitis

NCT03059446

This rollover study will provide open-label treatment with cenicriviroc and will assess the long-term safety of continued treatment with cenicriviroc in participants who participated in either the CENTAUR study 652-2-203 \[NCT02217475\] or the AURORA study \[NCT03028740\].

Nonalcoholic SteatohepatitisLiver CirrhosisNon-alcoholic Fatty Liver Disease

Tobira Therapeutics, Inc.167 participantsStarted Feb 2017

Dothan, Alabama, United States • Phoenix, Arizona, United States • Tucson, Arizona, United States +68 more locations

Biomarker-Driven Therapy With Nivolumab and Ipilimumab in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer Expressing AR-V7

Rollover Study of Cenicriviroc for the Treatment of Liver Fibrosis in Participants With Nonalcoholic Steatohepatitis

Find Trials by Condition in Baltimore

Study of Airway Pressure Release Ventilation and Intracranial Pressure in Patients With Severe Traumatic Brain Injury

Combination Chemotherapy in Treating Young Patients With Down Syndrome and Acute Myeloid Leukemia or Myelodysplastic Syndromes

Cerebral Autoregulation and Vasospasm in Patients With TBI

Imaging With a Radio Tracer to Guide VT Ablations

Safety and Dose Finding Study of Xigris in Hemodialysis Patients

A Multi-Center Trial to Study Acute Liver Failure in Adults

Study of PTC299 (Emvododstat) in Relapsed/Refractory Acute Leukemias

Study of the Combination of Panobinostat and Carfilzomib in Patients With Relapsed/Refractory Multiple Myeloma

Clinical Evaluation of a Daily Wear Silicone Hydrogel Lens

Safety and Efficacy Study of Adult Human Mesenchymal Stem Cells to Treat Acute Graft Versus Host Disease (GVHD)

IPH5401 (Anti-C5aR) in Combination With Durvalumab in Patients With Advanced Solid Tumors

Improving Critical Congenital Heart Disease Screening With Addition of Perfusion Measurements

SUSTAIN SWITCH: A Research Study to Compare Two Dose Schedules of Semaglutide Taken Once Weekly in People With Type 2 Diabetes

Safety, Tolerability, and Pharmacokinetic Study of ISIS ApoC-III Rx in Hypertriglyceridemia

Minocycline Hydrochloride in Reducing Chemotherapy-Induced Peripheral Neuropathy and Acute Pain in Patients With Breast Cancer Undergoing Treatment With Paclitaxel

Phase I/Ib Study of NIS793 in Combination With PDR001 in Patients With Advanced Malignancies.

Active Limb Orthosis for Home-Use Stroke Hemiparetic Gait Rehabilitation

Awareness, Care & Treatment In Obesity Management - An International Observation Among Teens (ACTION Teens)