Clinical Trials in Baltimore

Showing 4841-4860 of 17,842 trials

Working Memory and Physical Exercise Training in Patients With Mild Cognitive Impairment

NCT05948930

The prevalence of dementia will double in the next three decades in the U.S.; effective treatment or prevention for dementia is urgently needed. The current exploratory project aims to evaluate and understand how the brain and cognition may improve after a 12-week intervention that combines brain training and aerobic exercise training to improve brain function, both in those with mild cognitive impairment (some with possible prodromal Alzheimer's disease) and with healthy aging. Findings from this pilot project will guide and refine the development of a future larger clinical trial that aligns with the goals of the National Alzheimer's Plan of Action (NAPA), especially regarding "Prevent and Effectively Treat Alzheimer's Disease (AD) by 2025.

Mild Cognitive Impairment

University of Maryland, Baltimore90 participantsStarted Jan 2024

Baltimore, Maryland, United States

RECRUITINGNA< 1 mile

mPATH for Low-income Older Adults

NCT05935241

Although empirical research suggests that physical activity interventions benefit cognition and sleep in older adults in general, the possible benefit of physical activity is understudied in low-income older adults. The study aims to test the immediate and sustaining efficacy of an mHealth-facilitated Physical Activity Toward Health (mPATH) intervention on cognitive function and sleep in low-income older adults.

Sedentary TimeInsomniaCognitive Decline

Johns Hopkins University176 participantsStarted May 2024

Baltimore, Maryland, United States

Working Memory and Physical Exercise Training in Patients With Mild Cognitive Impairment

mPATH for Low-income Older Adults

Find Trials by Condition in Baltimore

Safety Study of AG-120 or AG-221 in Combination With Induction and Consolidation Therapy in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) With an IDH1 and/or IDH2 Mutation

Performance and Safety of a Digital Tool for Unsupervised Self-assessment of NMOSD

A Spatial Analysis of Hotspots and Targeted Injection Settings Pilot Intervention for HIV Prevention Among People Who Inject Drugs

AtRial Cardiopathy and Antithrombotic Drugs In Prevention After Cryptogenic Stroke

Multimodel Exercise and Weight Loss in Older Obese Veterans With Dysmobility

Effects of RAS on Gait in PD Patients With DBS

Long-term Follow-up of Subjects With Transfusion-Dependent β-Thalassemia (TDT) Treated With Ex Vivo Gene Therapy

Study of ASTX295 in Patients With Solid Tumors With Wild-Type p53

Electrical Stimulation Effect on Ankle Instability During Walking in Virtual Reality Setup

A Randomized, Controlled Trial to Evaluate the Safety and Effectiveness of the Route 92 Medical Reperfusion System (SUMMIT MAX)

Tezepelumab Efficacy and Safety in Reducing Oral Corticosteroid Use in Adults With Oral Corticosteroid Dependent Asthma

The ME&MG Digital Solution for Autonomous Assessment of Myasthenia Gravis

A Phase 3 Long-term Extension Study to Assess the Long-term Safety and Efficacy of Pegtibatinase Treatment in Participants ≥5 to ≤65 Years of Age With Classical Homocystinuria (HCU) (ENSEMBLE)

Calypso Knee System Clinical Study

FlowMet-R Blood Flow Measurement for the Diagnosis of Peripheral Artery Disease and Critical Limb Ischemia

Amivantamab in Adenoid Cystic Carcinoma

Study to Evaluate the Efficacy of a Probiotic in Infantile Colic Symptoms Relief

A Bioequivalence Study of Bimekizumab Given as 1x2mL or 2x1mL Subcutaneous Injection Using an Autoinjector in Healthy Study Participants