Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Johns Hopkins University
Age
18–80
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Males and Females who are 18 - 80 years old.
The participants will meet the standard diagnostic criteria for possible or probable ALS (based on El Escorial criteria). They will have been diagnosed by a Johns Hopkins Neurologist.
Healthy controls will be recruited by their interest in assisting the ALS population.
You may not be if
Forced vital capacity less than 60 % of predicted value.
Documented orthopnea on ALSFRS-R or otherwise unable to lie flat in an MRI scanner for the duration of the study.
Presence of pacemakers, aneurysm clips, shrapnel or otherwise disallowed implanted metallic devices for obtaining an MRI scan.
Pregnant or lactating females
Glomerular filtration rate (GFR) less than 60
History of: encephalitis, extensive white matter disease, intracranial hemorrhage, cerebral palsy, allergy to dye and/or IV drug abuse.
Clareo Health | Magnetic Resonance Imaging (MRI) in Amyotrophic Lateral Sclerosis (ALS)