Clinical Trials in Arizona

Showing 4681-4700 of 12,706 trials

Study to Evaluate Safety, PK, PD, Immunogenicity & Antitumor Activity of MSC-1 in Patients With Adv Solid Tumors

NCT03490669

This is a 2-part study to evaluate the safety and antitumor activity of MSC-1. MSC-1 is a first-in-class, humanized monoclonal antibody (IgG1) which binds to the immunosuppressive human cytokine Leukemia Inhibitory Factor (LIF), and is intended to treat adult patients with Advanced Solid Tumors. In part 1, multiple dose levels of MSC-1 in patients with advanced solid tumors will be studied to determine the recommended dose for further evaluation of safety and efficacy in Part 2.

Advanced Solid TumorsPancreatic CancerNon Small Cell Lung Cancer+1 more

AstraZeneca41 participantsStarted May 2018

Scottsdale, Arizona, United States • Grand Rapids, Michigan, United States • Middletown, New Jersey, United States +4 more locations

COMPLETEDPhase 331 miles

Anemia Studies in Chronic Kidney Disease: Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor Daprodustat-Non-Dialysis (ASCEND-ND)

NCT02876835

The purpose of this multi-center event-driven study in non-dialysis (ND) participants with anemia associated with chronic kidney disease (CKD) is to evaluate the safety and efficacy of daprodustat compared to darbepoetin alfa.

Anaemia

GlaxoSmithKline3,872 participantsStarted Sep 2016

Andalusia, Alabama, United States • Birmingham, Alabama, United States • Huntsville, Alabama, United States +571 more locations

Study to Evaluate Safety, PK, PD, Immunogenicity & Antitumor Activity of MSC-1 in Patients With Adv Solid Tumors

Anemia Studies in Chronic Kidney Disease: Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor Daprodustat-Non-Dialysis (ASCEND-ND)

Find Trials by Condition in Arizona

Palbociclib (PD-0332991) Combined With Fulvestrant In Hormone Receptor+ HER2-Negative Metastatic Breast Cancer After Endocrine Failure (PALOMA-3)

An Evaluation of the Efficacy and Safety of CSF-1 in the Temporary Correction of Presbyopia (NEAR-2)

Treatment Effects of Subcutaneous Injections of Pentosan Polysulfate Sodium vs Placebo in Participants With Knee OA Pain

Study of Trofinetide for the Treatment of Girls and Women With Rett Syndrome (LAVENDER™)

A Study Evaluating the Safety, Pharmacokinetics, and Clinical Effects of Intravenously Administered PT-112 Injection in Subjects With Advanced Solid Tumors and Subsequent Dose Expansion Cohorts

Study to Compare the Efficacy and Safety of Enzyme Replacement Therapies Avalglucosidase Alfa and Alglucosidase Alfa Administered Every Other Week in Patients With Late-onset Pompe Disease Who Have Not Been Previously Treated for Pompe Disease

Safety Surveillance Cohort Study of Vaccinia Vaccine (ACAM2000®)

An Open-Label, Single Arm Study of Obinutuzumab Short Duration Infusion in Patients With Previously Untreated Advanced Follicular Lymphoma

Anemia Studies in Chronic Kidney Disease (CKD): Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat in Non-Dialysis Subjects Evaluating Hemoglobin (Hgb) and Quality of Life (ASCEND-NHQ)

Evaluation of Product Performance of a New Silicone Hydrogel Multifocal Contact Lens

PREDICT Trial: PRospective Evaluation of NTM Disease In CysTic Fibrosis

Allogeneic Heart Stem Cells to Achieve Myocardial Regeneration

TAC/MTX vs. TAC/MMF/PTCY for Prevention of Graft-versus-Host Disease and Microbiome and Immune Reconstitution Study (BMT CTN 1703/1801)

Phase 2a Study of CAN-2409 With Standard Radiation Therapy for Malignant Glioma

Study of Edecesertib in Participants With Cutaneous Lupus Erythematosus (CLE)

Spiration Valves Against Standard Therapy

A Study of Atezolizumab in Locally Advanced or Metastatic Urothelial or Non-Urothelial Carcinoma of the Urinary Tract

Pilot Study of Nivolumab in Pediatric Patients With Hypermutant Cancers