Ulcerative Colitis Clinical Trials in Philadelphia

Showing 401-420 of 731 trials

A Phase 2 Open-label Pilot Study Evaluating MYK-461 in Subjects With Symptomatic Hypertrophic Cardiomyopathy and Left Ventricular Outflow Tract Obstruction

NCT02842242

The purpose of this phase 2 open-label pilot study is to evaluate the efficacy, pharmacokinetics (PK), pharmacodynamics (PD), safety, and tolerability of MYK-461 in subjects with symptomatic HCM and LVOT obstruction aged 18-70 years.

Cardiomyopathy, Hypertrophic ObstructiveLeft Ventricular Outflow Tract Obstruction

MyoKardia, Inc.21 participantsStarted Aug 2016

Scottsdale, Arizona, United States • New Haven, Connecticut, United States • Boston, Massachusetts, United States +4 more locations

COMPLETEDNA< 1 mile

Sleep and Daytime Use of Humidified Nasal High-flow Oxygen in COPD Outpatients

NCT03221387

Humidified Nasal High-flow with Oxygen (HNHF-O2) therapy has been reported to have acute beneficial effects in patients with hypoxemic respiratory failure who have been hospitalized. The usefulness of this therapy in the outpatient setting is unproven. This pilot study will test the feasibility of using this therapy in the outpatient setting and its effects on sleep.

Pulmonary Disease, Chronic ObstructiveHypercapniaHypoxia

Temple University30 participantsStarted Sep 2017

Philadelphia, Pennsylvania, United States

COMPLETED< 1 mile

Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)

NCT02365922

Frontotemporal Lobar Degeneration (FTLD) is the neuropathological term for a collection of rare neurodegenerative diseases that correspond to four main overlapping clinical syndromes: frontotemporal dementia (FTD), primary progressive aphasia (PPA), corticobasal degeneration syndrome (CBS) and progressive supranuclear palsy syndrome (PSPS). The goal of this study is to build a FTLD clinical research consortium to support the development of FTLD therapies for new clinical trials. The consortium, referred to as Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL), will be headquartered at UCSF and will partner with six patient advocacy groups to manage the consortium. Participants will be evaluated at 14 clinical sites throughout North America and a genetics core will genotype all individuals for FTLD associated genes.

FTLDProgressive Supranuclear Palsy (PSP)Frontotemporal Dementia (FTD)+9 more

University of California, San Francisco1,489 participantsStarted Sep 2014

Birmingham, Alabama, United States • Los Angeles, California, United States • San Diego, California, United States +14 more locations

A Phase 2 Open-label Pilot Study Evaluating MYK-461 in Subjects With Symptomatic Hypertrophic Cardiomyopathy and Left Ventricular Outflow Tract Obstruction

Sleep and Daytime Use of Humidified Nasal High-flow Oxygen in COPD Outpatients

Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)

Ulcerative Colitis Trials in Other Cities

Safety and Efficacy of ALD518 for Reducing Oral Mucositis in Head and Neck Cancer Subjects

Percutaneous Temporary Placement of a Phrenic Nerve Stimulator for Diaphragm Pacing (RESCUE1)

Bevacizumab and Intravenous or Intraperitoneal Chemotherapy in Treating Patients With Stage II-III Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer

Mucopolysaccharidosis (MPS) I, II, and VI Screening in a High-Risk Population With Previous Surgical Repair or Presence of Inguinal and/or Umbilical Hernia in Combination With Pediatric ENT Surgery (The HATT Project)

IOP and Medication Reduction in MIGS Procedures

A 12-week, Randomized, Double-masked, Parallel Group Comparison of Evening Dosing With Xalacom in Subjects With Glaucoma

Comparison of Latanoprost With Travoprost and Bimatoprost in Patients With Elevated IOP. A 12-weeks, Masked Evaluator, Phase IV Multi-center Study in the US

Buccal Versus Vaginal Misoprostol In Combination With Foley Bulb

Acceptance and Commitment Therapy in Improving Well-Being in Patients With Stage III-IV Cancer and Their Partners

An Extension Study of ABBV-8E12 in Progressive Supranuclear Palsy (PSP)

A 12-Week, Randomized, Double-Masked, Parallel Group Comparison Of Evening Dosing With Xalacom In Subjects With Glaucoma

Efficacy and Safety Study of SHP647 as Induction Therapy in Participants With Moderate to Severe Ulcerative Colitis

Automated Graduated CPAP (AGPAP) for Improved Adherence in Newly Diagnosed Obstructive Sleep Apnea (OSA) Patients

Day and Night Closed-loop in Young People With Type 1 Diabetes

Clinical Endpoint Bioequivalence Study of Test and Reference Inhalation Products in Patients With COPD With Device Robustness

Tadalafil for Pulmonary Hypertension Due to Chronic Lung Disease

Comparison of Pre- and Post-discharge Initiation of LCZ696 Therapy in HFrEF Patients After an Acute Decompensation Event

Other Conditions in Philadelphia