Rheumatoid Arthritis Clinical Trials

Showing 741-760 of 22,488 trials

Vagus Nerve Stimulation and Stress Reduction Training for Migraine

NCT03592329

This study design has two components: 1) a cross-sectional assessment of brain activity and inflammation in migraine patients compared to healthy controls and 2) an assessment of 8 weeks of a combination therapy approach to treating migraine.

Migraine

Massachusetts General Hospital193 participantsStarted Aug 2019

Charlestown, Massachusetts, United States

ACTIVE_NOT_RECRUITINGPHASE2

Acute GVHD Suppression Using Costimulation Blockade to Expand Non-malignant Transplant

NCT03924401

This trial will see if extended abatacept administration (combined with a standard regimen of tacrolimus and mycophenolate mofetil) will prevent acute and chronic graft-versus-host disease (GVHD) in children and adolescents receiving unrelated donor (URD) hematopoietic stem cell transplantation (HSCT), without compromising their engraftment or reconstitution of protective immunity to infection. The study will enroll 30 pediatric patients with serious non-malignant hematologic diseases (NMHD) undergoing URD HSCT. The trial will include patients with 7/8 donors and those with 8/8 (matched) donors. All participants will receive 8 doses of abatacept. Recruitment is expected to last for about 2 years and participants will be followed for up to 3 years.

Graft Versus Host Disease

Emory University30 participantsStarted Aug 2019

Birmingham, Alabama, United States • Wilmington, Delaware, United States • Atlanta, Georgia, United States +6 more locations

Vagus Nerve Stimulation and Stress Reduction Training for Migraine

Acute GVHD Suppression Using Costimulation Blockade to Expand Non-malignant Transplant

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