Rheumatoid Arthritis Clinical Trials

Showing 2821-2840 of 22,488 trials

Tailored Exercise Training Study Among Adults With HFpEF

NCT07223242

Heart failure with preserved ejection fraction (HFpEF) is associated with a high morbidity and mortality burden. There are limited pharmacological options available for the treatment of HFpEF. Exercise intolerance (EI) is the cardinal symptom of HFpEF, which manifests as dyspnea and fatigue. EI leads to functional deconditioning and reduced quality of life (QOL), both of which elevate risk of death and hospitalization in patients with HFpEF. Supervised exercised training is associated with improvements in exercise capacity and QOL in adults with HFpEF. However, supervised exercise has not been widely utilized for the treatment of HFpEF due to logistical and fiscal barriers. This study will investigate the effects of a remote exercise training intervention on exercise capacity and skeletal muscle composition in patients with HFpEF, or those at risk for it. In addition, it will compare four different lifestyle interventions for their effects on exercise capacity.

HFpEF - Heart Failure With Preserved Ejection FractionDiabetic Cardiomyopathies

University of Texas Southwestern Medical Center120 participantsStarted Feb 2025

Dallas, Texas, United States

Active Not RecruitingNA

Study of Posterior Cervical Stabilization System (PCSS) as Part of Circumferential Fusion to Treat Multilevel DDD

NCT04229017

This study will evaluate the safety and effectiveness of a device called "Posterior Cervical Stabilization System or PCSS" when used along with posterior cervical fusion (PCF) in combination with anterior cervical discectomy and fusion (ACDF) in the treatment of multi-level cervical degenerative disease.

Degenerative Disc Disease

Providence Medical Technology, Inc.236 participantsStarted Mar 2020

Phoenix, Arizona, United States • Encinitas, California, United States • Los Gatos, California, United States +14 more locations

Tailored Exercise Training Study Among Adults With HFpEF

Study of Posterior Cervical Stabilization System (PCSS) as Part of Circumferential Fusion to Treat Multilevel DDD

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