STrategies for Antithrombotic tReatment Following Transcatheter Edge-to-Edge Repair in Patients Without an Indication for Oral Anticoagulant

Exclusion Criteria

• •Severe renal impairment (creatinine clearance \< 15 mL/min or requiring dialysis).
• •Ongoing postoperative bleeding (defined as overt bleeding with a ≥3.0 g/dL drop in hemoglobin or requiring ≥3 units of blood transfusion), or vascular complications following the index TEER procedure.
• •Platelet count \< 50 × 10\^9 /L.
• •Need for reoperation due to complications of the index TEER procedure.
• •Recent ( \< 12 month) intracranial or intracerebral hemorrhage.
• •Recent ( \< 12 month) gastrointestinal ulcers or hemorrhage.
• •Hepatic disease with coagulopathy.(eg, Child-Pugh class B or C cirrhosis).
• •Allergy, intolerance, or contraindication to research drugs.
• •Participation in another investigational drug or device study within 30 days.
• •Indication for long-term OAC.
• •Absolute indication for dual antiplatelet therapy; (eg, recent PCI).
• •Life expectancy \< 12 months.
• •Pregnancy or breastfeeding.