Rheumatoid Arthritis Clinical Trials in Philadelphia

Showing 1581-1600 of 3,895 trials

Compare Two Copper IUDs: Mona Lisa NT Cu380 Mini and ParaGard

NCT03124160

This will be a multi-site, participant-blinded, randomized clinical trial. The investigators will randomize 1000 eligible participants in a 4:1 ratio to two different copper IUDs: 800 to Mona Lisa NT Cu380 Mini and 200 to ParaGard.

Healthy WomenFemale Contraception

FHI 3601,105 participantsStarted May 2017

Los Angeles, California, United States • Sacramento, California, United States • San Francisco, California, United States +13 more locations

COMPLETEDPhase 2< 1 mile

Investigating Otilimab in Patients With Severe Pulmonary COVID-19 Related Disease

NCT04376684

OSCAR (Otilimab in Severe COVID-19 Related Disease) is a multi-center, double-blind, randomized, placebo-controlled trial to assess the efficacy and safety of otilimab for the treatment of severe pulmonary COVID-19 related disease. The study is being conducted in 2 parts (Part 1 and Part 2). Otilimab is a human monoclonal anti-granulocyte macrophage colony stimulating factor (GM-CSF) antibody that has not previously been tested in participants with severe pulmonary COVID-19 related disease in Part 1. The aim of this study is to evaluate the benefit-risk of a single infusion of otilimab in the treatment of hospitalized participants with severe COVID-19 related pulmonary disease with new onset hypoxia requiring significant oxygen support or requiring early invasive mechanical ventilation (less than or equal to \[\<=\] 48 hours before dosing). Participants will be randomized to receive a single intravenous (IV) infusion of otilimab or placebo, in addition to standard of care.

Severe Acute Respiratory Syndrome

GlaxoSmithKline1,156 participantsStarted May 2020

Mobile, Alabama, United States • Little Rock, Arkansas, United States • Sacramento, California, United States +117 more locations

Compare Two Copper IUDs: Mona Lisa NT Cu380 Mini and ParaGard

Investigating Otilimab in Patients With Severe Pulmonary COVID-19 Related Disease

Rheumatoid Arthritis Trials in Other Cities

Mendelian Reverse Cholesterol Transport Study

Study to Evaluate Treatment Compliance, Efficacy and Safety of an Improved Deferasirox Formulation (Granules) in Pediatric Patients (2-<18 Years Old) With Iron Overload

Natural History Study of ENPP1 Deficiency and the Early-onset Form of ABCC6 Deficiency

Clinical Evaluation of the i-STAT TBI Test

Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Neurotrophic Keratitis Subjects

AI ENRICH - AI Detection of ICH

A Study to Evaluate Treatment Satisfaction With Erenumab in Participants With Migraine

A Study of Rilematovir (JNJ-53718678) in Adult Outpatients With Respiratory Syncytial Virus (RSV) Infection

A Study on the Immune Response and Safety Elicited by a Vaccine Against Respiratory Syncytial Virus (RSV) When Given Alone and Together With a Vaccine Against Influenza in Adults Aged 65 Years and Above

Evaluating Edema and Range of Motion Using Negative Pressure Therapy vs. Standard Surgical Dressing in Bilateral TKA

Safety and Tolerability of GTX-104 Compared with Oral Nimodipine in Patients with ASAH

BIO 300 Oral Suspension in Previously Hospitalized Long COVID Patients

ADVANCE- Automated Detection and Volumetric Assessment of ICH

Selinexor, Daratumumab, Carfilzomib and Dexamethasone for the Treatment of High-Risk, Recurrent or Refractory Multiple Myeloma

TelemEdiciNe-bAsed Cognitive TherapY for Migraines

Air Optix® Night and Day® Aqua Continuous Wear

A Study to Evaluate the Long-term Safety and Efficacy of Deucravacitinib in Participants With Crohn's Disease or Ulcerative Colitis

BD OneFlow CLPD Panel (BD OneFlow LST, and B-CLPD T1 to T4 Assays) on the BD FACSLyric System.

Other Conditions in Philadelphia