Rheumatoid Arthritis Clinical Trials in Philadelphia

Showing 2361-2380 of 3,347 trials

Noninvasive, Subharmonic Intra-Cardiac Pressure Measurement

NCT03243942

The fundamental hypothesis of this project is that real-time intracardiac pressures can be monitored and quantified noninvasively in humans using a novel contrast-enhanced ultrasound technique called subharmonic-aided pressure estimation (SHAPE).This study will use contrast echocardiography to assess the accuracy of SHAPE compared to simultaneously acquired intracardiac pressures measured invasively during cardiac catheterization. This study is designed to verify that contrast echocardiography using the SHAPE method, already proven in a canine model and tested in a human pilot study can be used as a surrogate for cardiac catheterization with sufficient accuracy to allow clinical applicability in humans.

Cardiac CatheterizationBlood PressureHeart Ventricles+2 more

Thomas Jefferson University56 participantsStarted Jun 2017

Philadelphia, Pennsylvania, United States

COMPLETEDPhase 3< 1 mile

The Plecanatide Irritable Bowel Syndrome With Constipation Study (IBS-C)

NCT02387359

This study in patients with IBS-C is a randomized, double-blind, placebo-controlled, parallel-group clinical trial with 12 weeks of study drug therapy.

Irritable Bowel Syndrome Characterized by Constipation

Bausch Health Americas, Inc.1,054 participantsStarted Dec 2014

Athens, Alabama, United States • Birmingham, Alabama, United States • Dothan, Alabama, United States +152 more locations

Noninvasive, Subharmonic Intra-Cardiac Pressure Measurement

The Plecanatide Irritable Bowel Syndrome With Constipation Study (IBS-C)

Rheumatoid Arthritis Trials in Other Cities

Benralizumab Efficacy in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With Exacerbation History

The Chimerix CMX001 Registry

A Study of CK-2017357 in Patients With Amyotrophic Lateral Sclerosis (ALS)

Handheld Vibrator Versus Topical Eye Drops as Anesthesia for Intravitreal Injections

Talc Outpatient Pleurodesis With Indwelling Catheter

Evaluation of the Efficacy, Durability, Safety, and Tolerability of RP-G28 in Patients With Lactose Intolerance

A Study to Compare Neostigmine vs Sugammadex in Length of PACU Stay in Patients Undergoing Sleeve Gastrectomy Surgery

A Study Investigating the Efficacy and Safety of Lampalizumab Intravitreal Injections in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration

A Phase 1/2 Study of AEB1102 in Patients With Arginase I Deficiency

SM-1 vs 2 Comparators and Placebo in Participants With a History of Transient Insomnia.

The Plecanatide Irritable Bowel Syndrome With Constipation Study (IBS-C)

A Phase 4 Trial Assessing the ImPact of Residual Inflammation Detected Via Imaging TEchniques, Drug Levels and Patient Characteristics on the Outcome of Dose TaperIng of Adalimumab in Clinical Remission Rheumatoid ArThritis (RA) Subjects

Validation of Brain Function Assessment Algorithm for mTBI/Concussion in College Athletes

Study to Evaluate Treatment of Dabrafenib Plus Trametinib in Subjects With BRAF Mutation-Positive Melanoma That Has Metastasized to the Brain

Efficacy, Tolerability and Safety of Early Introduction of Everolimus, Reduced Calcineurin Inhibitors and Early Steroid Elimination Compared to Standard CNI, Mycophenolate Mofetil and Steroid Regimen in Paediatric Renal Transplant Recipients

A Single-dose Study in Paediatric Patients Aged 2 to Less Than 18 Years With Secondary Hyperparathyroidism (sHPT) Receiving Haemodialysis

A Multicener, Postmarketing Study Evaluating the Transfer of Cimzia From the Mother to the Infant Via the Placenta

Efficacy and Safety Study of Deferiprone in Patients With Pantothenate Kinase-associated Neurodegeneration (PKAN)

Other Conditions in Philadelphia