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A Randomized, Double-blind, Placebo- and Active-controlled, Multicenter, Phase 3 Study to Assess the Efficacy and Safety of Filgotinib Administered for 52 Weeks Alone and in Combination With Methotrexate (MTX) to Subjects With Moderately to Severely Active Rheumatoid Arthritis Who Are Naïve to MTX Therapy
The primary objective of this study is to evaluate the effects of filgotinib in combination with methotrexate (MTX) versus MTX alone in adults with active rheumatoid arthritis (RA).
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Huntsville, Alabama, United States
Phoenix, Arizona, United States
Tucson, Arizona, United States
Covina, California, United States
Los Angeles, California, United States
Palm Desert, California, United States
Victorville, California, United States
Whittier, California, United States
DeBary, Florida, United States
Jacksonville, Florida, United States
Start Date
August 8, 2016
Primary Completion Date
October 5, 2018
Completion Date
May 8, 2019
Last Updated
June 1, 2021
1,252
ACTUAL participants
Filgotinib
DRUG
Placebo to match filgotinib
DRUG
MTX
DRUG
Placebo to match MTX
DRUG
Lead Sponsor
Gilead Sciences
Collaborators
NCT07484243
NCT06647069
Data Source & Attribution
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Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
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