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Clareo Health | Prostate Cancer Clinical Trials in Ohio | 521 Studies

Clinical Trials Prostate CancerOhio

Prostate Cancer Clinical Trials in Ohio

Find 521 clinical trials for prostate cancer near Ohio. Connect with research centers in your area.

All Prostate Cancer trials nationwide All trials in Ohio

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

Who can join

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Showing 341-360 of 521 trials

RecruitingStandard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate CancerThis phase III trial studies how well standard systemic therapy with or without definitive treatment (prostate removal surgery or radiation therapy) works in treating participants…NCT03678025·Gilbert, Arizona and 337 others

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Data from ClinicalTrials.govTerms

Active not recruitingA Study of Apalutamide (JNJ-56021927, ARN-509) Plus Androgen Deprivation Therapy (ADT) Versus ADT in Participants With mHSPCThe purpose of this study is to determine if the addition of apalutamide to ADT provides superior efficacy in improving radiographic progression-free survival (rPFS) or overall…NCT02489318·Homewood, Alabama and 219 others

Active not recruitingTTX-080 HLA-G Antagonist in Subjects With Advanced CancersTTX-080-001 is a Phase 1, open label, dose escalation and dose expansion clinical study to determine the safety, tolerability, and recommended Phase 2 dose of TTX-080 monotherapy…NCT04485013·Tucson, Arizona and 40 others

RecruitingTesting Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the BodyThis phase III trial compares the effect of adding carboplatin to the standard of care chemotherapy drug cabazitaxel versus cabazitaxel alone in treating prostate cancer that…NCT06470243·Fayetteville, Arkansas and 173 others

CompletedMEDI-522 in the Treatment of Patients With Metastatic Androgen-Independent Prostate CancerThe primary objectives of this study are: 1.NCT00072930·Hoover, Alabama and 56 others

Completed"REDUCE" - A Clinical Research Study To Reduce The Incidence Of Prostate Cancer In Men Who Are At Increased RiskThis 4-year study will compare how safe and effective an oral investigational medicine is (compared to placebo) in preventing the development of prostate cancer in men that are…NCT00056407·Birmingham, Alabama and 931 others

TerminatedHC-1119 Versus Enzalutamide in Metastatic Castration-Resistant Prostate Cancer (mCRPC)This study is a multinational Phase 3, randomized, double-blind, non-inferiority, efficacy and safety study of oral HC-1119 (80 mg/day) versus enzalutamide (160 mg/day) in…NCT03850795·Denver, Colorado and 57 others

Active not recruitingTesting the Addition of Darolutamide to Hormonal Therapy (Androgen Deprivation Therapy [ADT]) After Surgery for Men With High-Risk Prostate Cancer, The ERADICATE StudyThis phase III trial compares the effect of adding darolutamide to ADT versus ADT alone after surgery for the treatment of high-risk prostate cancer.NCT04484818·Duarte, California and 114 others

RecruitingThe Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)The Phase 2 monotherapy portion of this study is currently enrolling and will evaluate the efficacy and safety of PC14586 (INN rezatapopt) in participants with locally advanced or…NCT04585750·Irvine, California and 76 others

RecruitingSTereotActic Body Radiotherapy and 177Lutetium PSMA in Locally Advanced Prostate CancerThe goal of this clinical trial is to is to investigate if it is possible to lower the chance of cancer reoccurrence and also preserve quality of life by using the drug Pluvicto…NCT06574880·Cleveland, Ohio

TerminatedStudy of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid TumorsThis study is an open-label, international, multi-center, Phase 2 study in adult patients with recurrent, locally-advanced or metastatic solid tumors, which harbor the NRG1 gene…NCT04383210·Birmingham, Alabama and 41 others

TerminatedA Dose Escalation and Expansion Study of TRX518 in Combination With Cyclophosphamide Plus Avelumab in Advanced Solid TumorsThis is a Phase 1b/2a dose escalation and expansion, multi-center study to be conducted in 2 phases: * Phase 1b * Dose Escalation Part 1 (Doublet Therapy) * Dose Escalation…NCT03861403·Lafayette, Indiana and 3 others

Active not recruitingA Comparison of TULSA Procedure vs. Radical Prostatectomy in Participants With Localized Prostate CancerMen with localized, intermediate risk prostate cancer will be randomized to undergo either radical prostatectomy or the TULSA procedure, with a follow-up of 10 years in this…NCT05027477·Chandler, Arizona and 21 others

Active not recruitingTalazoparib + Enzalutamide vs. Enzalutamide Monotherapy in mCRPCThis study compares rPFS in men with mCRPC treated with talazoparib plus enzalutamide vs. enzalutamide after confirmation of the starting dose of talazoparib in combination with…NCT03395197·Anchorage, Alaska and 369 others

CompletedA Study of Nivolumab or Placebo in Combination With Docetaxel in Men With Advanced Castration-resistant Prostate CancerThe purpose of this study is to assess the safety and effectiveness of nivolumab with docetaxel in men with advanced castration resistant prostate cancer who have progressed after…NCT04100018·Mobile, Alabama and 292 others

CompletedEfficacy and Safety of Pembrolizumab (MK-3475) Plus Enzalutamide Plus Androgen Deprivation Therapy (ADT) Versus Placebo Plus Enzalutamide Plus ADT in Participants With Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) (MK-3475-991/KEYNOTE-991)This study will assess the efficacy and safety of pembrolizumab plus enzalutamide plus Androgen Deprivation Therapy (ADT) versus placebo plus enzalutamide plus ADT in participants…NCT04191096·Anchorage, Alaska and 233 others

RecruitingMDRT in Prostate Cancer Treated With Long-term Androgen Deprivation Therapy in the STAMPEDE Trial (METANOVA)The purpose of this study is to find out if giving radiation therapy (RT) to areas of metastatic prostate cancer at the time a participant is diagnosed will help control disease…NCT06150417·New York, New York and 2 others

CompletedA Study of Enzalutamide and LY3023414 in Men With Prostate CancerThe main purpose of this study is to evaluate the safety and effectiveness of the study drug known as LY3023414 in combination with enzalutamide in men with prostate cancer.NCT02407054·Homewood, Alabama and 35 others

Active not recruitingCopper Cu 64 PSMA I&T PET Imaging in Men With Newly Diagnosed Prostate CancerThis is a prospective, open-label Phase 3 study to evaluate copper Cu 64 PSMA I\&T injection for PET/CT imaging in patients with newly diagnosed unfavorable intermediate…NCT06235151·Homewood, Alabama and 42 others

RecruitingThis Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.This study will explore whether a combination of the investigational drug mevrometostat (PF-06821497) and enzalutamide will work better than taking enzalutamide alone in…NCT07028853·Huntsville, Alabama and 306 others

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