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Clareo Health | Pancreatic Cancer Clinical Trials in Pennsylvania | 414 Studies

Clinical Trials Pancreatic CancerPennsylvania

Pancreatic Cancer Clinical Trials in Pennsylvania

Find 414 clinical trials for pancreatic cancer near Pennsylvania. Connect with research centers in your area.

All Pancreatic Cancer trials nationwide All trials in Pennsylvania

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 61-80 of 414 trials

RecruitingPancreatic Adenocarcinoma Gene Environment Risk StudyAfter informed consent, participants will be asked to complete a medical/family history questionnaire and provide a blood sample.NCT00912717·Pittsburgh, Pennsylvania RecruitingAMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid TumorsThe purpose of this first-in-human study is to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary efficacy of AMG 410 when…NCT07094113·Duarte, California and 38 others

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Data from ClinicalTrials.govTerms

CompletedStudy of Pegilodecakin (LY3500518) With FOLFOX Compared to FOLFOX Alone Second-line Tx in Participants With Metastatic Pancreatic CancerTo compare the efficacy of pegilodecakin in combination with FOLFOX versus FOLFOX alone in participants with metastatic pancreatic cancer as measured by overall survival.NCT02923921·Gilbert, Arizona and 129 others

Active not recruitingTesting Cabozantinib in Patients With Advanced Pancreatic Neuroendocrine and Carcinoid TumorsThis phase III trial studies cabozantinib to see how well it works compared with placebo in treating patients with neuroendocrine or carcinoid tumors that may have spread from…NCT03375320·Anchorage, Alaska and 431 others

CompletedNT-I7 (Efineptakin Alfa) in Combination With Pembrolizumab in Participants With Advanced Solid TumorsThe main purposes of Phase 1b of this study are to determine the following in participants with advanced solid tumors: * Safety and tolerability of NT-I7 in combination with…NCT04332653·Tampa, Florida and 7 others

RecruitingORACLE: Observation of ResiduAl Cancer With Liquid Biopsy EvaluationThe purpose of ORACLE is to demonstrate the ability of a novel ctDNA assay developed by Guardant Health to detect recurrence in individuals treated for early-stage solid tumors.NCT05059444·Birmingham, Alabama and 56 others

CompletedLiposomal Irinotecan in Combination With Oxaliplatin, Leucovorin, and 5-fluorouracil for Patients With Locally Advanced Pancreatic Carcinoma:This is a phase II, single-arm, open-label, clinical study to investigate the efficacy and tolerability of a combination of liposomal irinotecan (nal-IRI) with oxaliplatin…NCT03861702·Chicago, Illinois and 3 others

Active not recruiting9-ING-41 in Patients With Advanced CancersGSK-3β is a potentially important therapeutic target in human malignancies.NCT03678883·Phoenix, Arizona and 65 others

TerminatedMaintenance Rucaparib in BRCA1, BRCA2 or PALB2 Mutated Pancreatic Cancer That Has Not Progressed on Platinum-based TherapyThe main purpose of this study is to look at the effectiveness, safety, and antitumor activity (preventing growth of the tumor) of the experimental study drug rucaparib (also…NCT03140670·Philadelphia, Pennsylvania

CompletedStudy to Evaluate Efficacy of CO-1.01 as Second Line Therapy for Gemcitabine-Refractory Stage IV Pancreatic AdenocarcinomaThe purpose of this study is to determine whether CO-1.01 is safe and effective for treating metastatic pancreatic cancer that did not respond to gemcitabine.NCT01233375·Tucson, Arizona and 12 others

CompletedEvaluation of Efficacy and Safety of Neoadjuvant Treatment With Pamrevlumab in Combination With Chemotherapy (Either Gemcitabine Plus Nab-paclitaxel or FOLFIRINOX) in Participants With Locally Advanced, Unresectable Pancreatic CancerThis is a Phase 3, randomized, double-blind trial to evaluate the efficacy and safety of neoadjuvant treatment with pamrevlumab or placebo in combination with either gemcitabine…NCT03941093·Phoenix, Arizona and 89 others

RecruitingAPOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 MutationThis phase II trial investigates how well the addition of olaparib following completion of surgery and chemotherapy works in treating patients with pancreatic cancer that has been…NCT04858334·Anchorage, Alaska and 454 others

TerminatedA Phase II Study of Gemcitabine and Erlotinib As Adjuvant Therapy In Patients With Resected Pancreatic CancerStudy Hypothesis: To estimate time to recurrence in pancreatic cancer patients treated with adjuvant erlotinib and gemcitabine.NCT00336700·Pittsburgh, Pennsylvania

CompletedA Study of Neoadjuvant Paricalcitol to Target the Microenvironment in Resectable Pancreatic CancerStudy of neoadjuvant paricalcitol to target the microenvironment in resectable pancreatic cancer to determine the effect of targeting the vitamin D metabolic program in the tumors…NCT02030860·Philadelphia, Pennsylvania

Active not recruitingStudy of RYZ101 Compared With SOC in Pts w Inoperable SSTR+ Well-differentiated GEP-NET That Has Progressed Following 177Lu-SSA TherapyThis study aims to determine the safety, pharmacokinetics (PK) and recommended Phase 3 dose (RP3D) of RYZ101 in Part 1, and the safety, efficacy, and PK of RYZ101 compared with…NCT05477576·Phoenix, Arizona and 53 others

CompletedCART-meso in Mesothelin Expressing CancersPhase I study to establish safety and feasibility of intravenously administered lentiviral transduced CART-meso cells administered with and without cyclophosphamide in a 3+3 dose…NCT02159716·Philadelphia, Pennsylvania

CompletedStudy of IDO Inhibitor in Combination With Gemcitabine and Nab-Paclitaxel in Patients With Metastatic Pancreatic CancerThis phase I/II trial is designed to efficiently identify the regimen limiting toxicity (RLT) and recommended phase 2 dose (RP2D) for the combination of the immunotherapeutic…NCT02077881·Palo Alto, California and 10 others

CompletedChemotherapy and Radiation Therapy Before Surgery Followed by Gemcitabine in Treating Patients with Pancreatic CancerThis pilot clinical trial studies combination chemotherapy and radiation therapy before surgery followed by gemcitabine hydrochloride in treating patients with pancreatic cancer.NCT01821612·La Jolla, California and 13 others

TerminatedA Study of TAK-500 With or Without Pembrolizumab in Adults With Select Locally Advanced or Metastatic Solid TumorsThis study is about TAK-500, given either alone or with pembrolizumab, in adults with select locally advanced or metastatic solid tumors.NCT05070247·Birmingham, Alabama and 11 others

CompletedPhase II Randomized Trial of mFOLFIRINOX +/- Ramucirumab in Advanced Pancreatic CancerThis is a phase II, multicenter, double-blinded, randomized, 2-arm trial evaluating the efficacy and safety of mFOLFIRINOX plus ramucirumab (Arm A) vs. mFOLFIRINOX plus placebo…NCT02581215·Scottsdale, Arizona and 7 others

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